HUMAN:IRF7

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	IRF7
Protein Name(s)	Interferon regulatory factor 7 IRF-7
External Links
UniProt	Q92985
EMBL	U73036 U53830 U53831 U53832 U53832 AF076494 CH471158 BC136555
CCDS	CCDS7703.1 CCDS7704.1 CCDS7705.1
RefSeq	NP_001563.2 NP_004020.1 NP_004022.2 XP_005252963.1 XP_006725200.1
UniGene	Hs.166120
PDB	2O61
PDBsum	2O61
ProteinModelPortal	Q92985
SMR	Q92985
BioGrid	109873
DIP	DIP-34895N
IntAct	Q92985
MINT	MINT-1202972
STRING	9606.ENSP00000329411
PhosphoSite	Q92985
DMDM	116242593
MaxQB	Q92985
PaxDb	Q92985
PRIDE	Q92985
Ensembl	ENST00000330243 ENST00000348655 ENST00000397566 ENST00000397574 ENST00000469048 ENST00000533182 ENST00000612534 ENST00000621391
GeneID	3665
KEGG	hsa:3665
UCSC	uc001lqg.3 uc001lqh.3 uc001lqi.3
CTD	3665
GeneCards	GC11M000602
HGNC	HGNC:6122
HPA	CAB017694
MIM	605047
neXtProt	NX_Q92985
PharmGKB	PA29921
eggNOG	NOG39245
GeneTree	ENSGT00760000119093
HOGENOM	HOG000111812
HOVERGEN	HBG105600
InParanoid	Q92985
KO	K09447
OMA	GWKTNFR
PhylomeDB	Q92985
TreeFam	TF328512
Reactome	REACT_24938 REACT_24970 REACT_25026 REACT_25078 REACT_25120 REACT_25148 REACT_25162
SignaLink	Q92985
ChiTaRS	IRF7
GeneWiki	IRF7
GenomeRNAi	3665
NextBio	14347
PRO	PR:Q92985
Proteomes	UP000005640 UP000005640
Bgee	Q92985
CleanEx	HS_IRF7
ExpressionAtlas	Q92985
Genevestigator	Q92985
GO	GO:0005737 GO:0005829 GO:0010008 GO:0005654 GO:0005634 GO:0003677 GO:0000982 GO:0000979 GO:0006974 GO:0019221 GO:0019043 GO:0016064 GO:0045087 GO:0032607 GO:0032608 GO:0060333 GO:0039530 GO:0002756 GO:2000110 GO:0000122 GO:0032727 GO:0032728 GO:0045944 GO:0045893 GO:0032481 GO:0060340 GO:0002819 GO:0050776 GO:0045655 GO:0034124 GO:0034127 GO:0032479 GO:0009615 GO:0034138 GO:0034142 GO:0034162 GO:0002224 GO:0006366 GO:0035666 GO:0045351 GO:0060337
Gene3D	1.10.10.10 2.60.200.10
InterPro	IPR019817 IPR001346 IPR019471 IPR017855 IPR008984 IPR011991
Pfam	PF00605 PF10401
PRINTS	PR00267
SMART	SM00348
SUPFAM	SSF49879
PROSITE	PS00601 PS51507

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0032728	positive regulation of interferon-beta production	PMID:22065573^[1]	ECO:0000315			P		Fig. 7BC	complete CACAO 3235
	GO:0005634	nucleus	PMID:22065573^[1]	ECO:0000314			C		Fig. 6D and Fig. 7A	complete CACAO 3236
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[2]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:19274049^[2]	ECO:0000255	match to sequence model evidence used in manual assertion	InterPro:IPR001346	F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000113	ECO:0005556	multiple sequence alignment evidence used in manual assertion	UniProtKB:P15314	F		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	PMID:21478870^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:19176627^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:22065573^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0032728	positive regulation of interferon-beta production	PMID:22065573^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:16127453^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032727	positive regulation of interferon-alpha production	PMID:16127453^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:17404045^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	PMID:12374802^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70434	P		Seeded From UniProt	complete
involved_in	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70434	P		Seeded From UniProt	complete
involved_in	GO:0032608	interferon-beta production	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70434	P		Seeded From UniProt	complete
involved_in	GO:0032607	interferon-alpha production	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70434	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	PMID:12374802^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0002819	regulation of adaptive immune response	PMID:17404045^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:17404045^[6]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_at:(SO:0001952)	Seeded From UniProt	complete
enables	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	PMID:17404045^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1096873 MGI:MGI:1859179 MGI:MGI:96395 MGI:MGI:96590 PANTHER:PTN000942746 RGD:2920 UniProtKB:O14896 UniProtKB:P10914 UniProtKB:P14316 UniProtKB:Q02556 UniProtKB:Q13568 UniProtKB:Q14653 UniProtKB:Q15306 UniProtKB:Q92985 ZFIN:ZDB-GENE-041114-13 ZFIN:ZDB-GENE-070912-330	C		Seeded From UniProt	complete
involved_in	GO:0002376	immune system process	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1096873 MGI:MGI:1350924 MGI:MGI:1859179 MGI:MGI:1859212 MGI:MGI:96395 MGI:MGI:96590 PANTHER:PTN000942747 UniProtKB:P10914 UniProtKB:P14316 UniProtKB:Q02556 UniProtKB:Q92985 ZFIN:ZDB-GENE-040718-367 ZFIN:ZDB-GENE-070912-330	P		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1859212 PANTHER:PTN000942746 UniProtKB:P10914 UniProtKB:P14316 UniProtKB:Q02556 UniProtKB:Q14653 UniProtKB:Q15306 UniProtKB:Q92985 ZFIN:ZDB-GENE-070912-330	F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0060337	type I interferon signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0045893	positive regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0045351	type I interferon biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0032608	interferon-beta production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0032607	interferon-alpha production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0032481	positive regulation of type I interferon production	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0016064	immunoglobulin mediated immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
involved_in	GO:0010468	regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	P		Seeded From UniProt	complete
enables	GO:0001158	enhancer sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	F		Seeded From UniProt	complete
enables	GO:0000987	proximal promoter sequence-specific DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	F		Seeded From UniProt	complete
enables	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70434 ensembl:ENSMUSP00000026571	F		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR019471 InterPro:IPR019817	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR019471 InterPro:IPR019817	P		Seeded From UniProt	complete
enables	GO:0044212	transcription regulatory region DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001346	F		Seeded From UniProt	complete
involved_in	GO:0009615	response to virus	PMID:9786932^[9] PMID:21490621^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006366	transcription by RNA polymerase II	PMID:9315633^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:9786932^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:9786932^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:9315633^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000110	negative regulation of macrophage apoptotic process	PMID:21490621^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050776	regulation of immune response	PMID:21490621^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045655	regulation of monocyte differentiation	PMID:21490621^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045087	innate immune response	PMID:17404045^[6]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0039530	MDA-5 signaling pathway	PMID:16979567^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032728	positive regulation of interferon-beta production	PMID:16979567^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032727	positive regulation of interferon-alpha production	PMID:16979567^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032479	regulation of type I interferon production	PMID:21490621^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019043	establishment of viral latency	PMID:21490621^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:16979567^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060337	type I interferon signaling pathway	Reactome:R-HSA-909733	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060333	interferon-gamma-mediated signaling pathway	Reactome:R-HSA-877300	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	Reactome:R-HSA-936964 Reactome:R-HSA-9013973	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032481	positive regulation of type I interferon production	Reactome:R-HSA-1834949	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	Reactome:R-HSA-975188 Reactome:R-HSA-975118 Reactome:R-HSA-975106	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-975188 Reactome:R-HSA-975106 Reactome:R-HSA-9604487 Reactome:R-HSA-933538 Reactome:R-HSA-933533 Reactome:R-HSA-933531 Reactome:R-HSA-933525 Reactome:R-HSA-918232 Reactome:R-HSA-918229 Reactome:R-HSA-9013979 Reactome:R-HSA-9013978 Reactome:R-HSA-177671 Reactome:R-HSA-168933 Reactome:R-HSA-166271 Reactome:R-HSA-166245 Reactome:R-HSA-1031716 Reactome:R-HSA-1028821 Reactome:R-HSA-1028816 Reactome:R-HSA-1015702	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-9604487 Reactome:R-HSA-933536 Reactome:R-HSA-933531 Reactome:R-HSA-177671 Reactome:R-HSA-1028820 Reactome:R-HSA-1028819 Reactome:R-HSA-1028816	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0051	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0002376	immune system process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0391	P		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0045087	innate immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0399	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Siednienko, J et al. (2011) Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1. J. Biol. Chem. 286 44750-63 PubMed GONUTS page
↑ ^2.0 ^2.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
↑ Schoggins, JW et al. (2011) A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472 481-5 PubMed GONUTS page
↑ Saira, K et al. (2009) The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 and consequently inhibits beta interferon promoter activity. J. Virol. 83 3977-81 PubMed GONUTS page
↑ ^5.0 ^5.1 Kawai, T et al. (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6 981-8 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 Sgarbanti, M et al. (2007) IRF-7: new role in the regulation of genes involved in adaptive immunity. Ann. N. Y. Acad. Sci. 1095 325-33 PubMed GONUTS page
↑ ^7.0 ^7.1 Caillaud, A et al. (2002) Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding. J. Biol. Chem. 277 49417-21 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 Au, WC et al. (1998) Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes. J. Biol. Chem. 273 29210-7 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 ^10.4 ^10.5 Ning, S et al. (2011) IRF7: activation, regulation, modification and function. Genes Immun. 12 399-414 PubMed GONUTS page
↑ ^11.0 ^11.1 Zhang, L & Pagano, JS (1997) IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency. Mol. Cell. Biol. 17 5748-57 PubMed GONUTS page
↑ ^12.0 ^12.1 ^12.2 ^12.3 Honda, K et al. (2006) Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 25 349-60 PubMed GONUTS page

[PMID:22065573-1] 1.0 ^1.1 ^1.2 ^1.3 Siednienko, J et al. (2011) Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1. J. Biol. Chem. 286 44750-63 PubMed GONUTS page

[PMID:19274049-2] 2.0 ^2.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page

[PMID:21478870-3] Schoggins, JW et al. (2011) A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472 481-5 PubMed GONUTS page

[PMID:19176627-4] Saira, K et al. (2009) The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) associates with interferon regulatory factor 7 and consequently inhibits beta interferon promoter activity. J. Virol. 83 3977-81 PubMed GONUTS page

[PMID:16127453-5] 5.0 ^5.1 Kawai, T et al. (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6 981-8 PubMed GONUTS page

[PMID:17404045-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 Sgarbanti, M et al. (2007) IRF-7: new role in the regulation of genes involved in adaptive immunity. Ann. N. Y. Acad. Sci. 1095 325-33 PubMed GONUTS page

[PMID:12374802-7] 7.0 ^7.1 Caillaud, A et al. (2002) Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding. J. Biol. Chem. 277 49417-21 PubMed GONUTS page

[PMID:21873635-8] 8.0 ^8.1 ^8.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:9786932-9] 9.0 ^9.1 ^9.2 Au, WC et al. (1998) Characterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genes. J. Biol. Chem. 273 29210-7 PubMed GONUTS page

[PMID:21490621-10] 10.0 ^10.1 ^10.2 ^10.3 ^10.4 ^10.5 Ning, S et al. (2011) IRF7: activation, regulation, modification and function. Genes Immun. 12 399-414 PubMed GONUTS page

[PMID:9315633-11] 11.0 ^11.1 Zhang, L & Pagano, JS (1997) IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency. Mol. Cell. Biol. 17 5748-57 PubMed GONUTS page

[PMID:16979567-12] 12.0 ^12.1 ^12.2 ^12.3 Honda, K et al. (2006) Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 25 349-60 PubMed GONUTS page

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HUMAN:IRF7

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