HUMAN:CXAR

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	CXADR (synonyms: CAR)
Protein Name(s)	Coxsackievirus and adenovirus receptor CAR hCAR CVB3-binding protein Coxsackievirus B-adenovirus receptor HCVADR
External Links
UniProt	P78310
EMBL	U90716 Y07593 AF169366 AF169360 AF169361 AF169362 AF169363 AF169364 AF169365 AF200465 AY072910 AY072911 AY072912 AF242865 AF242862 AF242864 GU474812 CR617256 BT019876 AK313526 AP000963 AP000967 CH471079 BC003684 BC010536 AF124598
CCDS	CCDS33519.1 CCDS56204.1 CCDS56205.1 CCDS56206.1 CCDS56207.1
RefSeq	NP_001193992.1 NP_001193993.1 NP_001193994.1 NP_001193995.1 NP_001329.1
UniGene	Hs.627078
PDB	1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW 3J6L 3J6M 3J6N 3J6O
PDBsum	1EAJ 1F5W 1JEW 1KAC 1P69 1P6A 1RSF 2J12 2J1K 2NPL 2W9L 2WBW 3J6L 3J6M 3J6N 3J6O
ProteinModelPortal	P78310
SMR	P78310
BioGrid	107905
IntAct	P78310
MINT	MINT-111007
STRING	9606.ENSP00000284878
MEROPS	I43.001
PhosphoSite	P78310
DMDM	6685351
MaxQB	P78310
PaxDb	P78310
PRIDE	P78310
DNASU	1525
Ensembl	ENST00000284878 ENST00000356275 ENST00000400165 ENST00000400166 ENST00000400169
GeneID	1525
KEGG	hsa:1525
UCSC	uc002ykh.2 uc002yki.3 uc010gld.2 uc010gle.2
CTD	1525
GeneCards	GC21P018884
HGNC	HGNC:2559
HPA	CAB005103 HPA003342 HPA030411 HPA030412
MIM	602621
neXtProt	NX_P78310
PharmGKB	PA27055
eggNOG	NOG83644
GeneTree	ENSGT00760000119145
HOGENOM	HOG000111222
HOVERGEN	HBG105787
InParanoid	P78310
KO	K06788
OMA	VGNKKIQ
OrthoDB	EOG7MH0Z1
PhylomeDB	P78310
TreeFam	TF330875
Reactome	REACT_11152 REACT_12051
ChiTaRS	CXADR
EvolutionaryTrace	P78310
GeneWiki	Coxsackie_virus_and_adenovirus_receptor
GenomeRNAi	1525
NextBio	35491112
PRO	PR:P78310
Proteomes	UP000005640
Bgee	P78310
CleanEx	HS_CXADR
Genevestigator	P78310
GO	GO:0001669 GO:0005912 GO:0016327 GO:0016323 GO:0044297 GO:0030054 GO:0005911 GO:0005576 GO:0005615 GO:0030175 GO:0030426 GO:0005887 GO:0014704 GO:0045121 GO:0031594 GO:0043005 GO:0005634 GO:0005886 GO:0043234 GO:0005923 GO:0008013 GO:0050839 GO:0071253 GO:0042802 GO:0005178 GO:0030165 GO:0005102 GO:0001618 GO:0031532 GO:0086067 GO:0007596 GO:0048739 GO:0045216 GO:0051607 GO:0010669 GO:0046629 GO:0008354 GO:0007507 GO:0007157 GO:0034109 GO:0050900 GO:0007005 GO:0030593 GO:0050776 GO:0070633 GO:0016032
Gene3D	2.60.40.10
InterPro	IPR007110 IPR013783 IPR003599 IPR003598 IPR013106
Pfam	PF07686
SMART	SM00409 SM00408
PROSITE	PS50835

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005737	cytoplasm	PMID:22003382^[1]	ECO:0000314			C		Figure 2E shows CAR expression in cytoplasm (white arrows) in two different cell types	complete CACAO 6767
	GO:0005923	tight junction	PMID:22003382^[1]	ECO:0000314			C		Figure 2E shows CAR protein is expressed at tight junctions (Red Arrows) in specific cell type	complete CACAO 6768
part_of	GO:0005913	cell-cell adherens junction	PMID:25468996^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0098904	regulation of AV node cell action potential	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
involved_in	GO:0086072	AV node cell-bundle of His cell adhesion involved in cell communication	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P	results_in_development_of:(EMAPA:17337)\|results_in_development_of:(EMAPA:17340)\|results_in_development_of:(EMAPA:16696)\|results_in_development_of:(EMAPA:16546)	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P	results_in_development_of:(EMAPA:16819)\|results_in_development_of:(EMAPA:16818)\|results_in_development_of:(EMAPA:16823)\|results_in_development_of:(EMAPA:16826)\|results_in_development_of:(EMAPA:16337)\|results_in_development_of:(EMAPA:16341)\|results_in_development_of:(EMAPA:16353)	Seeded From UniProt	complete
enables	GO:0086082	cell adhesive protein binding involved in AV node cell-bundle of His cell communication	PMID:18636119^[3]	ECO:0000305	curator inference used in manual assertion	GO:0086072	F		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	PMID:22003382^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:22003382^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0086067	AV node cell to bundle of His cell communication	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
enables	GO:0071253	connexin binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	F		Seeded From UniProt	complete
involved_in	GO:0070633	transepithelial transport	PMID:15800062^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0050839	cell adhesion molecule binding	PMID:12869515^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q86YT9	F		Seeded From UniProt	complete
enables	GO:0050839	cell adhesion molecule binding	PMID:15800062^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q86YT9	F		Seeded From UniProt	complete
involved_in	GO:0048739	cardiac muscle fiber development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
involved_in	GO:0046629	gamma-delta T cell activation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
involved_in	GO:0045216	cell-cell junction organization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:17675666^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0044297	cell body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	C		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:17675666^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	C		Seeded From UniProt	complete
involved_in	GO:0031532	actin cytoskeleton reorganization	PMID:17675666^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030593	neutrophil chemotaxis	PMID:15800062^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	C		Seeded From UniProt	complete
part_of	GO:0030175	filopodium	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	C		Seeded From UniProt	complete
enables	GO:0030165	PDZ domain binding	PMID:15364909^[7]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O75970	F		Seeded From UniProt	complete
part_of	GO:0016327	apicolateral plasma membrane	PMID:15364909^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	PMID:20361046^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0010669	epithelial structure maintenance	PMID:15304526^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008354	germ cell migration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
enables	GO:0008013	beta-catenin binding	PMID:12297051^[10]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P35222	F		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
involved_in	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	PMID:12869515^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	PMID:15800062^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007005	mitochondrion organization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	P		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	PMID:15800062^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005912	adherens junction	PMID:12297051^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005911	cell-cell junction	PMID:17675666^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005911	cell-cell junction	PMID:20235596^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:9096397^[12]	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:9096397^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:16780588^[13]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	PMID:12869515^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P13612	F		Seeded From UniProt	complete
part_of	GO:0001669	acrosomal vesicle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97792	C		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0001618	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:14978041^[14]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0034109	homotypic cell-cell adhesion	PMID:11734628^[15]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	PMID:11316797^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0014704	intercalated disc	PMID:15533241^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	PMID:11734628^[15]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002202)	Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:14978041^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P78310-5	F		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:14978041^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P78310-4	F		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:14978041^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P78310-3	F		Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:15533241^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0014704	intercalated disc	PMID:15533241^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	PMID:14978041^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:14978041^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:14978041^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P78310-1	F		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	PMID:14978041^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:14978041^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:14978041^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P78310-1	F		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	PMID:14978041^[14]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:14978041^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:14978041^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P78310-1	F		Seeded From UniProt	complete
involved_in	GO:0050900	leukocyte migration	Reactome:R-HSA-202733	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050776	regulation of immune response	Reactome:R-HSA-198933	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-199093	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P		Seeded From UniProt	complete
enables	GO:0001618	virus receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1183	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
part_of	GO:0005923	bicellular tight junction	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0796 UniProtKB-SubCell:SL-0265	C		Seeded From UniProt	complete
part_of	GO:0005912	adherens junction	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0009	C		Seeded From UniProt	complete
part_of	GO:0016323	basolateral plasma membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0026	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Borovjagin, AV et al. (2011) Adenovirus gene transfer to amelogenesis imperfecta ameloblast-like cells. PLoS ONE 6 e24281 PubMed GONUTS page
↑ Guo, Z et al. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Sci Signal 7 rs7 PubMed GONUTS page
↑ Lim, BK et al. (2008) Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J. Clin. Invest. 118 2758-70 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 Zen, K et al. (2005) Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol. Biol. Cell 16 2694-703 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Moog-Lutz, C et al. (2003) JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood 102 3371-8 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 Shono, A et al. (2007) Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes. J. Am. Soc. Nephrol. 18 2525-33 PubMed GONUTS page
↑ ^7.0 ^7.1 Coyne, CB et al. (2004) The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction. J. Biol. Chem. 279 48079-84 PubMed GONUTS page
↑ Excoffon, KJ et al. (2010) Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia. PLoS ONE 5 e9909 PubMed GONUTS page
↑ Excoffon, KJ et al. (2004) A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth. J. Cell. Sci. 117 4401-9 PubMed GONUTS page
↑ ^10.0 ^10.1 Walters, RW et al. (2002) Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape. Cell 110 789-99 PubMed GONUTS page
↑ Kesisoglou, F et al. (2010) Adenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: the coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transduction. Mol. Pharm. 7 619-29 PubMed GONUTS page
↑ ^12.0 ^12.1 Tomko, RP et al. (1997) HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc. Natl. Acad. Sci. U.S.A. 94 3352-6 PubMed GONUTS page
↑ Hu, YH et al. (2006) Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. BMC Genomics 7 155 PubMed GONUTS page
↑ ^14.00 ^14.01 ^14.02 ^14.03 ^14.04 ^14.05 ^14.06 ^14.07 ^14.08 ^14.09 ^14.10 ^14.11 ^14.12 Dörner, A et al. (2004) Alternatively spliced soluble coxsackie-adenovirus receptors inhibit coxsackievirus infection. J. Biol. Chem. 279 18497-503 PubMed GONUTS page
↑ ^15.0 ^15.1 Cohen, CJ et al. (2001) The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proc. Natl. Acad. Sci. U.S.A. 98 15191-6 PubMed GONUTS page
↑ Cohen, CJ et al. (2001) Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sorting. J. Biol. Chem. 276 25392-8 PubMed GONUTS page
↑ ^17.0 ^17.1 ^17.2 Shaw, CA et al. (2004) Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs. BMC Cell Biol. 5 42 PubMed GONUTS page

[PMID:22003382-1] 1.0 ^1.1 ^1.2 ^1.3 Borovjagin, AV et al. (2011) Adenovirus gene transfer to amelogenesis imperfecta ameloblast-like cells. PLoS ONE 6 e24281 PubMed GONUTS page

[PMID:25468996-2] Guo, Z et al. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Sci Signal 7 rs7 PubMed GONUTS page

[PMID:18636119-3] Lim, BK et al. (2008) Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J. Clin. Invest. 118 2758-70 PubMed GONUTS page

[PMID:15800062-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 Zen, K et al. (2005) Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol. Biol. Cell 16 2694-703 PubMed GONUTS page

[PMID:12869515-5] 5.0 ^5.1 ^5.2 Moog-Lutz, C et al. (2003) JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells. Blood 102 3371-8 PubMed GONUTS page

[PMID:17675666-6] 6.0 ^6.1 ^6.2 ^6.3 Shono, A et al. (2007) Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes. J. Am. Soc. Nephrol. 18 2525-33 PubMed GONUTS page

[PMID:15364909-7] 7.0 ^7.1 Coyne, CB et al. (2004) The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction. J. Biol. Chem. 279 48079-84 PubMed GONUTS page

[PMID:20361046-8] Excoffon, KJ et al. (2010) Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia. PLoS ONE 5 e9909 PubMed GONUTS page

[PMID:15304526-9] Excoffon, KJ et al. (2004) A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growth. J. Cell. Sci. 117 4401-9 PubMed GONUTS page

[PMID:12297051-10] 10.0 ^10.1 Walters, RW et al. (2002) Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape. Cell 110 789-99 PubMed GONUTS page

[PMID:20235596-11] Kesisoglou, F et al. (2010) Adenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: the coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transduction. Mol. Pharm. 7 619-29 PubMed GONUTS page

[PMID:9096397-12] 12.0 ^12.1 Tomko, RP et al. (1997) HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc. Natl. Acad. Sci. U.S.A. 94 3352-6 PubMed GONUTS page

[PMID:16780588-13] Hu, YH et al. (2006) Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. BMC Genomics 7 155 PubMed GONUTS page

[PMID:14978041-14] 14.00 ^14.01 ^14.02 ^14.03 ^14.04 ^14.05 ^14.06 ^14.07 ^14.08 ^14.09 ^14.10 ^14.11 ^14.12 Dörner, A et al. (2004) Alternatively spliced soluble coxsackie-adenovirus receptors inhibit coxsackievirus infection. J. Biol. Chem. 279 18497-503 PubMed GONUTS page

[PMID:11734628-15] 15.0 ^15.1 Cohen, CJ et al. (2001) The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proc. Natl. Acad. Sci. U.S.A. 98 15191-6 PubMed GONUTS page

[PMID:11316797-16] Cohen, CJ et al. (2001) Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sorting. J. Biol. Chem. 276 25392-8 PubMed GONUTS page

[PMID:15533241-17] 17.0 ^17.1 ^17.2 Shaw, CA et al. (2004) Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs. BMC Cell Biol. 5 42 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

HUMAN:CXAR

Contents

Annotations

Notes

References

a

b

c

d

e

f

g

h

i

l

m

n

o

p

r

s

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools