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HUMAN:AQP1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) AQP1 (synonyms: CHIP28)
Protein Name(s) Aquaporin-1

AQP-1 Aquaporin-CHIP Urine water channel Water channel protein for red blood cells and kidney proximal tubule

External Links
UniProt P29972
EMBL M77829
U41517
U41518
S73482
AK309608
AY953319
AC004691
AC005155
AB451275
AB451402
CH471073
BC022486
AF480415
CCDS CCDS5431.1
CCDS55096.1
CCDS55097.1
CCDS55098.1
PIR A41616
I52366
RefSeq NP_001171989.1
NP_001171990.1
NP_001171991.1
NP_932766.1
UniGene Hs.76152
PDB 1FQY
1H6I
1IH5
PDBsum 1FQY
1H6I
1IH5
ProteinModelPortal P29972
SMR P29972
BioGrid 106854
DIP DIP-29607N
IntAct P29972
MINT MINT-1439356
STRING 9606.ENSP00000311165
DrugBank DB00819
GuidetoPHARMACOLOGY 688
TCDB 1.A.8.8.1
PhosphoSite P29972
DMDM 267412
PaxDb P29972
PRIDE P29972
DNASU 358
Ensembl ENST00000311813
ENST00000409611
ENST00000409899
ENST00000441328
GeneID 358
KEGG hsa:358
UCSC uc003tbv.2
CTD 358
GeneCards GC07P030894
HGNC HGNC:633
HPA CAB001707
HPA019206
MIM 107776
110450
neXtProt NX_P29972
PharmGKB PA24918
eggNOG COG0580
GeneTree ENSGT00760000119223
HOGENOM HOG000288286
HOVERGEN HBG000312
InParanoid P29972
KO K09864
OMA FNNHWIF
OrthoDB EOG7N8ZWD
PhylomeDB P29972
TreeFam TF312940
Reactome REACT_121329
REACT_121380
REACT_23826
REACT_24023
ChiTaRS AQP1
EvolutionaryTrace P29972
GeneWiki Aquaporin_1
GenomeRNAi 358
NextBio 1497
PRO PR:P29972
Proteomes UP000005640
Bgee P29972
CleanEx HS_AQP1
ExpressionAtlas P29972
Genevestigator P29972
GO GO:0045177
GO:0016324
GO:0043679
GO:0009925
GO:0016323
GO:0005903
GO:0031526
GO:0005737
GO:0070062
GO:0005887
GO:0031965
GO:0005634
GO:0005886
GO:0042383
GO:0020003
GO:0008519
GO:0035379
GO:0015168
GO:0005223
GO:0030184
GO:0005267
GO:0015079
GO:0022857
GO:0015250
GO:0005372
GO:0072488
GO:0015696
GO:0015701
GO:0048593
GO:0035378
GO:0015670
GO:0098655
GO:0006884
GO:0019725
GO:0071474
GO:0071320
GO:0071280
GO:0071549
GO:0070301
GO:0071456
GO:0071241
GO:0071260
GO:0071288
GO:0071732
GO:0071300
GO:0071472
GO:0033554
GO:0034644
GO:0033326
GO:0006182
GO:0051458
GO:0030950
GO:0003094
GO:0015793
GO:0042538
GO:0021670
GO:0044241
GO:0085018
GO:0072220
GO:0072239
GO:0072232
GO:0072230
GO:0050891
GO:0043066
GO:0043154
GO:0030185
GO:0042476
GO:0030157
GO:0045766
GO:0010634
GO:0048146
GO:0010592
GO:0046878
GO:0071805
GO:0006813
GO:0070295
GO:0003097
GO:0042493
GO:0043627
GO:0033363
GO:0019233
GO:0044281
GO:0035377
GO:0055085
GO:0006833
GO:0042060
Gene3D 1.20.1080.10
InterPro IPR023271
IPR023274
IPR000425
IPR022357
PANTHER PTHR19139
Pfam PF00230
PRINTS PR02013
PR00783
SUPFAM SSF81338
TIGRFAMs TIGR00861
PROSITE PS00221

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0070062

extracellular exosome

PMID:23533145[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:19056867[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(UBERON:0001088)

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

PMID:15326289[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0001088)

Seeded From UniProt

complete

involved_in

GO:0085018

maintenance of symbiont-containing vacuole by host

PMID:18665841[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071732

cellular response to nitric oxide

PMID:14561230[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071549

cellular response to dexamethasone stimulus

PMID:16711029[6]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071474

cellular hyperosmotic response

PMID:11922632[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071472

cellular response to salt stress

PMID:18509662[8]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071456

cellular response to hypoxia

PMID:18275976[9]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071320

cellular response to cAMP

PMID:18538351[10]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071320

cellular response to cAMP

PMID:17636236[11]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071300

cellular response to retinoic acid

PMID:19424603[12]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071300

cellular response to retinoic acid

PMID:12051745[13]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071288

cellular response to mercury ion

PMID:12172703[14]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071288

cellular response to mercury ion

PMID:12745312[15]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071288

cellular response to mercury ion

PMID:9321919[16]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071288

cellular response to mercury ion

PMID:8584435[17]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071288

cellular response to mercury ion

PMID:7491270[18]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071280

cellular response to copper ion

PMID:8584435[17]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071280

cellular response to copper ion

PMID:7491270[18]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071260

cellular response to mechanical stimulus

PMID:19268465[19]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071241

cellular response to inorganic substance

PMID:14561230[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070301

cellular response to hydrogen peroxide

PMID:19424603[12]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050891

multicellular organismal water homeostasis

PMID:17645239[20]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048146

positive regulation of fibroblast proliferation

PMID:16565507[21]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046878

positive regulation of saliva secretion

PMID:15727941[22]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046878

positive regulation of saliva secretion

PMID:9096382[23]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045766

positive regulation of angiogenesis

PMID:18275976[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0045177

apical part of cell

PMID:14675051[24]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0043154

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

PMID:21215257[25]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0002306)

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:16565507[21]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042493

response to drug

PMID:12172703[14]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042476

odontogenesis

PMID:12522663[26]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0042383

sarcolemma

PMID:17409744[27]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0035379

carbon dioxide transmembrane transporter activity

PMID:17012249[28]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0035378

carbon dioxide transmembrane transport

PMID:17012249[28]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035377

transepithelial water transport

PMID:12766090[29]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034644

cellular response to UV

PMID:19424603[12]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0033326

cerebrospinal fluid secretion

PMID:16814974[30]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0031965

nuclear membrane

PMID:17645239[20]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0031526

brush border membrane

PMID:9013443[31]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030950

establishment or maintenance of actin cytoskeleton polarity

PMID:19584911[32]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030185

nitric oxide transport

PMID:16682607[33]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0030184

nitric oxide transmembrane transporter activity

PMID:16682607[33]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030157

pancreatic juice secretion

PMID:12801959[34]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0022857

transmembrane transporter activity

PMID:17012249[28]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0021670

lateral ventricle development

PMID:16133142[35]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

colocalizes_with

GO:0020005

symbiont-containing vacuole membrane

PMID:18665841[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0020003

symbiont-containing vacuole

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02013

C

Seeded From UniProt

complete

involved_in

GO:0019725

cellular homeostasis

PMID:19268465[19]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:12801959[34]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:16133142[35]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:12766090[29]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:17890385[36]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:9096382[23]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:9013443[31]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:18617525[37]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:16814974[30]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:12801959[34]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:9013443[31]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:16133142[35]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:12766090[29]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:9096382[23]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:18617525[37]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0015793

glycerol transport

PMID:8584435[17]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015793

glycerol transport

PMID:7491270[18]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015696

ammonium transport

PMID:19273840[38]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015696

ammonium transport

PMID:16574458[39]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015670

carbon dioxide transport

PMID:12745312[15]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015670

carbon dioxide transport

PMID:19273840[38]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015670

carbon dioxide transport

PMID:16574458[39]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:19424603[12]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:12801959[34]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015168

glycerol transmembrane transporter activity

PMID:8584435[17]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015168

glycerol transmembrane transporter activity

PMID:7491270[18]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015079

potassium ion transmembrane transporter activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02013

F

Seeded From UniProt

complete

part_of

GO:0009925

basal plasma membrane

PMID:17409744[27]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008519

ammonium transmembrane transporter activity

PMID:19273840[38]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006884

cell volume homeostasis

PMID:11922632[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:19424603[12]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:14561230[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:12172703[14]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:9321919[16]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:8584435[17]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:12766090[29]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:7521540[40]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:8576117[41]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

PMID:11914159[42]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006813

potassium ion transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q02013

P

Seeded From UniProt

complete

involved_in

GO:0019934

cGMP-mediated signaling

PMID:14561230[5]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005903

brush border

PMID:16814974[30]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005903

brush border

PMID:16133142[35]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:19545896[43]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:19584911[32]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:17645239[20]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:9321919[16]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:14521551[44]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:17012249[28]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:12002613[45]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:18509662[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:18392839[46]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

NOT|part_of

GO:0005886

plasma membrane

PMID:7544358[47]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:12051745[13]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:7491270[18]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:19545896[43]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:16814974[30]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:17645239[20]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:18509662[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:17645239[20]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:14561230[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:12172703[14]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:9321919[16]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:9096382[23]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:8584435[17]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:12766090[29]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:7521540[40]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:8576117[41]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005372

water transmembrane transporter activity

PMID:11914159[42]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005267

potassium channel activity

PMID:11914159[42]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005223

intracellular cGMP-activated cation channel activity

PMID:14561230[5]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0003097

renal water transport

PMID:9096382[23]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0035379

carbon dioxide transmembrane transporter activity

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002709505
UniProtKB:P29972
ZFIN:ZDB-GENE-030131-7764

F

Seeded From UniProt

complete

involved_in

GO:0035378

carbon dioxide transmembrane transport

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000440666
UniProtKB:P29972

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG13270
FB:FBgn0000180
FB:FBgn0015872
MGI:MGI:103201
PANTHER:PTN000440616
RGD:2143
UniProtKB:P06624

C

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG13270
FB:FBgn0015872
MGI:MGI:107387
MGI:MGI:1096865
MGI:MGI:96990
PANTHER:PTN000440616
RGD:2141
RGD:2143
RGD:3090
UniProtKB:P06624
UniProtKB:P29972
UniProtKB:P30301
UniProtKB:P41181
UniProtKB:P55064
UniProtKB:P55087
UniProtKB:Q5A1Z4
ZFIN:ZDB-GENE-030131-7764
ZFIN:ZDB-GENE-040801-41

F

Seeded From UniProt

complete

enables

GO:0015168

glycerol transmembrane transporter activity

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002709505
RGD:2141
UniProtKB:P29972

F

Seeded From UniProt

complete

enables

GO:0008519

ammonium transmembrane transporter activity

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002709505
UniProtKB:P29972
ZFIN:ZDB-GENE-030131-7764

F

Seeded From UniProt

complete

involved_in

GO:0006972

hyperosmotic response

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002709505
RGD:2141
UniProtKB:P29972

P

Seeded From UniProt

complete

involved_in

GO:0003097

renal water transport

PMID:21873635[48]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103201
PANTHER:PTN002709506
UniProtKB:P29972

P

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:18202181[49]

ECO:0000269

experimental evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:1510932[50]

ECO:0000269

experimental evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:14701836[51]

ECO:0000269

experimental evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:1373524[52]

ECO:0000269

experimental evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015250

water channel activity

PMID:11034202[53]

ECO:0000269

experimental evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:25416956[54]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P29972

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:17632520[55]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P29972

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005223

P

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015079

P

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005267

P

Seeded From UniProt

complete

involved_in

GO:0072488

ammonium transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008519

P

Seeded From UniProt

complete

involved_in

GO:0072488

ammonium transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008519

P

Seeded From UniProt

complete

involved_in

GO:0098655

cation transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005223

P

Seeded From UniProt

complete

enables

GO:0015267

channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000425

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000425

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000425

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:1722319[56]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0015701

bicarbonate transport

Reactome:R-HSA-1247673
Reactome:R-HSA-1237044

ECO:0000304

author statement supported by traceable reference used in manual assertion


P

Seeded From UniProt

complete

involved_in

GO:0006833

water transport

Reactome:R-HSA-432047

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-HSA-507870
Reactome:R-HSA-507868
Reactome:R-HSA-432054
Reactome:R-HSA-432010
Reactome:R-HSA-1247649
Reactome:R-HSA-1237042

ECO:0000304

author statement supported by traceable reference used in manual assertion






C

Seeded From UniProt

complete

involved_in

GO:0003091

renal water homeostasis

Reactome:R-HSA-432040

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

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  3. Pisitkun, T et al. (2004) Identification and proteomic profiling of exosomes in human urine. Proc. Natl. Acad. Sci. U.S.A. 101 13368-73 PubMed GONUTS page
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