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DANRE:Q90XD1

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) HMG-box transcription factor Sox10 (ECO:0000313 with EMBL:AAK84872.1)

Sox10 protein (ECO:0000313 with EMBL:AAI63868.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000100237)

External Links
UniProt Q90XD1
EMBL CU695115
BC163868
BC163883
AF402677
RefSeq NP_571950.1
UniGene Dr.83682
SMR Q90XD1
Ensembl ENSDART00000112979
GeneID 140616
KEGG dre:140616
CTD 6663
ZFIN ZDB-GENE-011207-1
GeneTree ENSGT00760000118988
HOGENOM HOG000108876
HOVERGEN HBG002061
KO K09270
OMA MANMEPF
OrthoDB EOG7Q2N5K
PhylomeDB Q90XD1
NextBio 20797027
PRO PR:Q90XD1
Proteomes UP000000437
GO GO:0048484
GO:0010001
GO:0048839
GO:0030318
GO:0050768
GO:0014032
GO:0001755
GO:0048709
GO:0071600
GO:0048840
GO:0010628
GO:0014044
GO:0014037
GO:0048752
Gene3D 1.10.30.10
InterPro IPR009071
IPR022151
Pfam PF00505
PF12444
SMART SM00398
SUPFAM SSF47095
PROSITE PS50118

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0021772

olfactory bulb development

PMID:23539289[1]

IMP: Inferred from Mutant Phenotype

P

Fig 5 for Sox10

complete
CACAO 7308

GO:0001755

neural crest cell migration

PMID:15817223[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1190

P

Seeded From UniProt

complete

GO:0001755

neural crest cell migration

PMID:15817223[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-136

P

Seeded From UniProt

complete

GO:0010001

glial cell differentiation

PMID:19570850[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-090826-2
ZFIN:ZDB-MRPHLNO-090825-1

P

Seeded From UniProt

complete

GO:0010001

glial cell differentiation

PMID:19570850[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-090825-1
ZFIN:ZDB-MRPHLNO-090825-3

P

Seeded From UniProt

complete

GO:0010628

positive regulation of gene expression

PMID:19527705[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-990910-11

P

Seeded From UniProt

complete

GO:0014032

neural crest cell development

PMID:10631172[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1565

P

Seeded From UniProt

complete

GO:0014032

neural crest cell development

PMID:11684650[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-136

P

Seeded From UniProt

complete

GO:0014037

Schwann cell differentiation

PMID:17065232[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070131-8

P

Seeded From UniProt

complete

GO:0014044

Schwann cell development

PMID:18176560[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080402-2

P

Seeded From UniProt

complete

GO:0014044

Schwann cell development

PMID:18176560[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080430-1

P

Seeded From UniProt

complete

GO:0014044

Schwann cell development

PMID:19955371[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110803-1

P

Seeded From UniProt

complete

GO:0021772

olfactory bulb development

PMID:23539289[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0030318

melanocyte differentiation

PMID:22562198[10]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-011207-1
ZFIN:ZDB-GENO-121004-5

P

Seeded From UniProt

complete

GO:0048484

enteric nervous system development

PMID:15817223[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1190

P

Seeded From UniProt

complete

GO:0048484

enteric nervous system development

PMID:15817223[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-136

P

Seeded From UniProt

complete

GO:0048709

oligodendrocyte differentiation

PMID:17065232[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070131-8

P

Seeded From UniProt

complete

GO:0048752

semicircular canal morphogenesis

PMID:19132125[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1565

P

Seeded From UniProt

complete

GO:0048839

inner ear development

PMID:19132125[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-980202-1565
ZFIN:ZDB-MRPHLNO-070130-7
ZFIN:ZDB-MRPHLNO-090422-7
ZFIN:ZDB-MRPHLNO-090422-8
ZFIN:ZDB-MRPHLNO-090422-9

P

Seeded From UniProt

complete

GO:0048839

inner ear development

PMID:19132125[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-980202-1565
ZFIN:ZDB-MRPHLNO-070130-7
ZFIN:ZDB-MRPHLNO-090422-9

P

Seeded From UniProt

complete

GO:0048839

inner ear development

PMID:19132125[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-980202-1565
ZFIN:ZDB-MRPHLNO-090422-7
ZFIN:ZDB-MRPHLNO-090422-8

P

Seeded From UniProt

complete

GO:0048839

inner ear development

PMID:19132125[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1565

P

Seeded From UniProt

complete

GO:0048840

otolith development

PMID:19132125[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1565

P

Seeded From UniProt

complete

GO:0050768

negative regulation of neurogenesis

PMID:15677337[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-291

P

Seeded From UniProt

complete

GO:0071600

otic vesicle morphogenesis

PMID:9007247[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Saxena, A et al. (2013) Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish. Elife 2 e00336 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Elworthy, S et al. (2005) Phox2b function in the enteric nervous system is conserved in zebrafish and is sox10-dependent. Mech. Dev. 122 659-69 PubMed GONUTS page
  3. 3.0 3.1 Drerup, CM et al. (2009) Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation. Development 136 2623-32 PubMed GONUTS page
  4. Curran, K et al. (2009) Foxd3 controls melanophore specification in the zebrafish neural crest by regulation of Mitf. Dev. Biol. 332 408-17 PubMed GONUTS page
  5. Kelsh, RN & Eisen, JS (2000) The zebrafish colourless gene regulates development of non-ectomesenchymal neural crest derivatives. Development 127 515-25 PubMed GONUTS page
  6. Dutton, KA et al. (2001) Zebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates. Development 128 4113-25 PubMed GONUTS page
  7. 7.0 7.1 Carney, TJ et al. (2006) A direct role for Sox10 in specification of neural crest-derived sensory neurons. Development 133 4619-30 PubMed GONUTS page
  8. 8.0 8.1 Kucenas, S et al. (2008) CNS-derived glia ensheath peripheral nerves and mediate motor root development. Nat. Neurosci. 11 143-51 PubMed GONUTS page
  9. Kucenas, S et al. (2009) A selective glial barrier at motor axon exit points prevents oligodendrocyte migration from the spinal cord. J. Neurosci. 29 15187-94 PubMed GONUTS page
  10. An, M & Henion, PD (2012) The zebrafish sf3b1b460 mutant reveals differential requirements for the sf3b1 pre-mRNA processing gene during neural crest development. Int. J. Dev. Biol. 56 223-37 PubMed GONUTS page
  11. 11.0 11.1 11.2 11.3 11.4 11.5 Dutton, K et al. () A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle. Dis Model Mech 2 68-83 PubMed GONUTS page
  12. López-Schier, H & Hudspeth, AJ (2005) Supernumerary neuromasts in the posterior lateral line of zebrafish lacking peripheral glia. Proc. Natl. Acad. Sci. U.S.A. 102 1496-501 PubMed GONUTS page
  13. Malicki, J et al. (1996) Mutations affecting development of the zebrafish ear. Development 123 275-83 PubMed GONUTS page