Category:Team Numero Uno

ESAT-6 inhibits phagosome maturation through translocation of the cytosol. By stopping the secretion of ESAT-6, the movement of M. tuberculosis was stopped.

Figure 7 shows that the protein down regulates early T cell activation markers

Figure 3, figure 4 (D-F). The protein suppresses important cytokines vital for host defenses.

Figure 4 (D-F)

Heat shock protein (hspX) is a molecular chaperone which has been shown to increase latency of infection and slow the growth of Mycobacterium tuberculosis.

Figure 7

Figure 4 (D)

Figure 4 (E)

Figure 2

Figure 3 (B)Addition of CFP-10 stimulated neutrophils to produce more O2.

Figure 3 (A)Cells migrated more with higher concentration CFP-10.