GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Cacao

Jump to: navigation, search
GO:0050868negative regulation of T cell activationPMID:19265145IDA: Inferred from Direct Assay P
This annotation made on page: MYCTU:ESXA
By: Abbey.Steckler (group Team Numero Uno) on 2016-04-06 08:19:09 CDT.




You must be logged in to challenge this annotation.

Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeHeidi.Larson.1,
Team Grapes of Staph
2016-04-04 20:19:22 CDT

Abbey, it might be worth pointing out the difference between 7A and 7B. The difference between the two figures is the T cell activation marker looked at in each case. Figure 7A was CD25 and Figure 7B was CD69. It may help if you mention that the highest concentration of ESAT-6 (3.3uM) elicited this response significantly in both circumstances.

1
Private
Assessment
Suzialeksander2016-04-06 20:28:01 CDTYou need to be an instructor to view these notes.Unacceptable
Unique/Original
Private
Assessment
Suzialeksander2016-04-06 20:08:46 CDTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
Suzialeksander2016-04-06 20:07:41 CDT

So, it might help to think of it like this: Currently, your annotation says the M tuberculosis protein ESAT-6 downregulates the activation of M tuberculosis T cells... I wasn't really aware that bacteria had T cells. Maybe there's a better term??

Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Public
Assessment
DanielRenfro2016-04-04 20:19:22 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Suzialeksander2016-04-01 09:43:27 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Private
Assessment
Min.lorna2016-03-29 19:40:55 CDTYou need to be an instructor to view these notes.Flagged
Private
Assessment
Min.lorna2016-03-26 17:04:41 CDTYou need to be an instructor to view these notes.Flagged