User:Heidi.Larson.1

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	ALIFS:LUXI	2016-02-22 10:59:37 CST	GO:0061579 N-acyl homoserine lactone synthase activity (F)	PMID:17827287	ECO:0000317 genomic context evidence used in manual assertion		challenge
unacceptable	VIBF1:LUXS	2016-03-07 22:56:13 CST	GO:0003700 transcription factor activity, sequence-specific DNA binding (F)	other:17827287	ECO:0000314 direct assay evidence used in manual assertion	Fig. 2 shows direct binding of LuxR protein to promoters of genes of Lux operon	challenge
updatedbyinstructor	VIBF1:Q5E268	2016-03-29 03:26:00 CDT	GO:0006083 acetate metabolic process (P)	PMID:18487321	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig 5, Table 2	challenge
updatedbyinstructor	VIBF1:Q5E615	2016-04-12 05:10:27 CDT	GO:0008218 bioluminescence (P)	PMID:24056099	ECO:0000316 genetic interaction evidence used in manual assertion	Fig. 2 shows that the ainR mutant has decreased luminescence. This decreased luminescence can be mediated with the addition of C8-AHL. This shows that ainR in V. fischeri acts almost identically to luxN in V. harveyi.	challenge

acceptable:0
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Heidi.Larson.1

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
unacceptable	Brice.Sondrol, Team Spartan	ENTFC:VANX	GO:0010628 - positive regulation of gene expression (P)	PMID:8981985	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 3
unacceptable	KonaKuaiwa, Team Sandy Konas	SCHPO:CLR4	GO:1900111 - positive regulation of histone H3-K9 dimethylation (P)	PMID:26889830	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1
unacceptable	Jkane94, Team MIA	HUMAN:CDK9	GO:0050729 - positive regulation of inflammatory response (P)	PMID:26859911	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 3
unacceptable	Jonathan.Yuen, Team Not Very Creative	MYCTU:ESXA	GO:0032689 - negative regulation of interferon-gamma production (P)	PMID:19265145	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 2
unacceptable	Abbey.Steckler, Team Numero Uno	MYCTU:ESXA	GO:0050868 - negative regulation of T cell activation (P)	PMID:19265145	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
unacceptable	Abbey.Steckler, Team Numero Uno	MYCTU:ESXA	GO:0044414 - suppression of host defenses by symbiont (P)	PMID:19265145	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
unacceptable	Margalit.R.Balaban, Team The Herd	STAAU:SARA	GO:0006508 - proteolysis (P)	PMID:25257373	ECO:0000316 genetic interaction evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Tracy.Pham, Team Espresso my genes	HUMAN:NLRC4	GO:0097202 - activation of cysteine-type endopeptidase activity (P)	PMID:15882992	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2
unacceptable	Hannah.Wagner, Team I'm bringing sexy bacterium	STRPY:Q54958	GO:0045916 - negative regulation of complement activation (P)	PMID:8557634	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Heidi.Larson.1, Team Grapes of Staph	VIBF1:Q5E615	GO:0008218 - bioluminescence (P)	PMID:24056099	ECO:0000316 genetic interaction evidence used in manual assertion	challenge	C: 3 fixed by Heidi.Larson.1
updatedbyinstructor	Heidi.Larson.1, Team Grapes of Staph	VIBF1:Q5E268	GO:0006083 - acetate metabolic process (P)	PMID:18487321	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2 fixed by Heidi.Larson.1
unacceptable	Ttran13, Team Asian persuasian	MOUSE:CTGF	GO:0014028 - notochord formation (P)	PMID:23839921	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1

2 annotations fixed by Heidi.Larson.1

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