Category:GO:0061684 ! chaperone-mediated autophagy

id: GO:0061684

name: chaperone-mediated autophagy
namespace: biological_process
def: "The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded." [GOC:pad, GOC:PARL, PMID:22743996, PMID:23434281]
synonym: "CASA" BROAD [PMID:23434281]
synonym: "chaperone-assisted selective autophagy" EXACT [PMID:23434281]
synonym: "CMA" BROAD [PMID:22743996]
xref: Wikipedia:Chaperone-mediated_autophagy
is_a: GO:0006914 ! autophagy
is_a: GO:0030163 ! protein catabolic process
relationship: has_part: GO:0005102 ! signaling receptor binding
relationship: has_part: GO:0051087 ! protein-folding chaperone binding
relationship: has_part: GO:0140597 ! protein carrier chaperone

AmiGO <GOterm>GO:0061684</GOterm>
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