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Category:GO:0042267 ! natural killer cell mediated cytotoxicity
name: natural killer cell mediated cytotoxicity
namespace: biological_process
def: "The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors." [GOC:add, GOC:pr]
comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.
synonym: "killer activity" RELATED []
synonym: "natural killer cell mediated cell death" EXACT []
synonym: "natural killer cell mediated cell killing" EXACT []
synonym: "natural killer cell mediated cytolysis" RELATED []
synonym: "natural killer-cell mediated cytolysis" RELATED []
synonym: "NK cell mediated cell death" EXACT []
synonym: "NK cell mediated cell killing" EXACT []
synonym: "NK cell mediated cytolysis" RELATED []
synonym: "NK cell mediated cytotoxicity" EXACT []
is_a: GO:0001909 ! leukocyte mediated cytotoxicity
is_a: GO:0002228 ! natural killer cell mediated immunity
AmiGO
<GOterm>GO:0042267</GOterm>
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This category has the following 4 subcategories, out of 4 total.
