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Category:GO:0006342 ! chromatin silencing

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DAG for GO:0006342id: GO:0006342

name: chromatin silencing
namespace: biological_process
alt_id: GO:0016440
def: "Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin." [GOC:mah, PMID:10219245]
comment: Note that this process is the opposite of chromatin-mediated maintenance of transcription. This regulation is exemplified by members of the Polycomb group, which maintain the inactive state of homeotic gene transcription.
synonym: "chromatin-mediated maintenance of transcriptional inactivation" EXACT []
synonym: "chromatin-mediated silencing" EXACT []
synonym: "heterochromatic silencing" RELATED []
synonym: "TGS" EXACT []
synonym: "transcriptional gene silencing" EXACT []
is_a: GO:0006325 ! chromatin organization
is_a: GO:0016458 ! gene silencing
is_a: GO:0045814 ! negative regulation of gene expression, epigenetic
is_a: GO:0045892 ! negative regulation of transcription, DNA-templated


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