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DROME:A1Z9S5

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided. (synonyms: Su(var)2-HP2-RB (ECO:0000313 with EMBL:ACH92539.1))
Protein Name(s) RE12383p (ECO:0000313 with EMBL:ACH92539.1)

Su(Var)2-HP2, isoform B (ECO:0000313 with EMBL:AAO41391.1)

External Links
UniProt A1Z9S5
EMBL AE013599
BT044474
RefSeq NP_788354.1
UniGene Dm.624
EnsemblMetazoa FBtr0087502
GeneID 36621
KEGG dme:Dmel_CG12864
UCSC CG12864-RB
CTD 36621
FlyBase FBgn0026427
eggNOG NOG239182
OrthoDB EOG7C5M79
GenomeRNAi 36621
NextBio 799542
Proteomes UP000000803
GO GO:0000775
GO:0000793
GO:0000792
GO:0005720
GO:0005700
GO:0003677
GO:0051276
GO:0016458
GO:0031507
GO:0007076
GO:0022008

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0000793

condensed chromosome

PMID:16980400[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0051276

chromosome organization

PMID:16980400[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031507

heterochromatin assembly

PMID:16980400[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016458

gene silencing

PMID:12376620[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005720

nuclear heterochromatin

PMID:12376620[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000792

heterochromatin

PMID:27514026[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007076

mitotic chromosome condensation

PMID:16980400[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0000792

heterochromatin

PMID:14579245[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000775

chromosome, centromeric region

PMID:14579245[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005700

polytene chromosome

PMID:12815720[5]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:12815720[5]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Shaffer, CD et al. (2006) The large isoform of Drosophila melanogaster heterochromatin protein 2 plays a critical role in gene silencing and chromosome structure. Genetics 174 1189-204 PubMed GONUTS page
  2. 2.0 2.1 Shaffer, CD et al. (2002) Heterochromatin protein 2 (HP2), a partner of HP1 in Drosophila heterochromatin. Proc. Natl. Acad. Sci. U.S.A. 99 14332-7 PubMed GONUTS page
  3. Swenson, JM et al. (2016) The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic. Elife 5 PubMed GONUTS page
  4. 4.0 4.1 Zhimulev, IF & Belyaeva, ES (2003) Intercalary heterochromatin and genetic silencing. Bioessays 25 1040-51 PubMed GONUTS page
  5. 5.0 5.1 McNairn, AJ & Gilbert, DM (2003) Epigenomic replication: linking epigenetics to DNA replication. Bioessays 25 647-56 PubMed GONUTS page