GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0005852 ! eukaryotic translation initiation factor 3 complex
name: eukaryotic translation initiation factor 3 complex
namespace: cellular_component
def: "A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]
synonym: "eIF-3" EXACT []
synonym: "eIF3" EXACT []
is_a: GO:0032991 ! protein-containing complex
relationship: part_of: GO:0005737 ! cytoplasm
AmiGO
<GOterm>GO:0005852</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
Child Terms
This category has the following 2 subcategories, out of 2 total.
