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DROME:EIF3I

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Trip1 (ECO:0000255 with HAMAP-Rule:MF_03008) (synonyms: DmTRIP, eif3-S2 (ECO:0000255 with HAMAP-Rule:MF_03008))
Protein Name(s) Eukaryotic translation initiation factor 3 subunit I (ECO:0000255 with HAMAP-Rule:MF_03008)

eIF3i (ECO:0000255 with HAMAP-Rule:MF_03008) Eukaryotic translation initiation factor 3 subunit 2 (ECO:0000255 with HAMAP-Rule:MF_03008) TRIP-1 homolog eIF-3-beta (ECO:0000255 with HAMAP-Rule:MF_03008)

External Links
UniProt O02195
EMBL U90930
AE014134
AY118527
RefSeq NP_523478.1
UniGene Dm.2654
ProteinModelPortal O02195
SMR O02195
BioGrid 59895
DIP DIP-18772N
IntAct O02195
MINT MINT-1576694
PaxDb O02195
PRIDE O02195
EnsemblMetazoa FBtr0079053
GeneID 33710
KEGG dme:Dmel_CG8882
UCSC CG8882-RA
CTD 33710
FlyBase FBgn0015834
eggNOG COG2319
GeneTree ENSGT00630000089849
InParanoid O02195
KO K03246
OMA KATVCAF
OrthoDB EOG7PVWPK
PhylomeDB O02195
Reactome REACT_205240
REACT_207008
REACT_207218
REACT_213100
REACT_215632
REACT_225982
SignaLink O02195
GenomeRNAi 33710
NextBio 784905
PRO PR:O02195
Proteomes UP000000803
Bgee O02195
GO GO:0016282
GO:0033290
GO:0005852
GO:0005875
GO:0003743
GO:0001731
GO:0006446
GO:0006413
Gene3D 2.130.10.10
HAMAP MF_03008
InterPro IPR027525
IPR015943
IPR001680
IPR019775
IPR017986
Pfam PF00400
SMART SM00320
SUPFAM SSF50978
PROSITE PS00678
PS50082
PS50294

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006413

translational initiation

PMID:17392269[1]

ECO:0000314

P

Figure 4 characterizes the association of Drosophila eIF3 to the 40S ribosomal subunit during normal and active translation.

complete
CACAO 4671

enables

GO:0003743

translation initiation factor activity

PMID:10908586[2]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0006413

translational initiation

PMID:10908586[2]

ECO:0000250

sequence similarity evidence used in manual assertion

P

Seeded From UniProt

Missing: with/from

part_of

GO:0005852

eukaryotic translation initiation factor 3 complex

PMID:10908586[2]

ECO:0000250

sequence similarity evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

enables

GO:0003743

translation initiation factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027525

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027525

C

Seeded From UniProt

complete

part_of

GO:0005852

eukaryotic translation initiation factor 3 complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027525

C

Seeded From UniProt

complete

part_of

GO:0005852

eukaryotic translation initiation factor 3 complex

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107081

C

Seeded From UniProt

complete

involved_in

GO:0002183

cytoplasmic translational initiation

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107081

P

Seeded From UniProt

complete

enables

GO:0003743

translation initiation factor activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107081

F

Seeded From UniProt

complete

involved_in

GO:0001732

formation of cytoplasmic translation initiation complex

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107081

P

Seeded From UniProt

complete

part_of

GO:0016282

eukaryotic 43S preinitiation complex

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107081

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107081

C

Seeded From UniProt

complete

part_of

GO:0033290

eukaryotic 48S preinitiation complex

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000107081

C

Seeded From UniProt

complete

enables

GO:0003743

translation initiation factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0396

F

Seeded From UniProt

complete

involved_in

GO:0006413

translational initiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0396

P

Seeded From UniProt

complete

involved_in

GO:0006412

translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0648

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Andersen, DS & Leevers, SJ (2007) The essential Drosophila ATP-binding cassette domain protein, pixie, binds the 40 S ribosome in an ATP-dependent manner and is required for translation initiation. J. Biol. Chem. 282 14752-60 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lasko, P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J. Cell Biol. 150 F51-6 PubMed GONUTS page