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DROME:EIF3I

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Trip1 (ECO:0000255 with HAMAP-Rule:MF_03008) (synonyms: DmTRIP, eif3-S2 (ECO:0000255 with HAMAP-Rule:MF_03008))
Protein Name(s) Eukaryotic translation initiation factor 3 subunit I (ECO:0000255 with HAMAP-Rule:MF_03008)

eIF3i (ECO:0000255 with HAMAP-Rule:MF_03008) Eukaryotic translation initiation factor 3 subunit 2 (ECO:0000255 with HAMAP-Rule:MF_03008) TRIP-1 homolog eIF-3-beta (ECO:0000255 with HAMAP-Rule:MF_03008)

External Links
UniProt O02195
EMBL U90930
AE014134
AY118527
RefSeq NP_523478.1
UniGene Dm.2654
ProteinModelPortal O02195
SMR O02195
BioGrid 59895
DIP DIP-18772N
IntAct O02195
MINT MINT-1576694
PaxDb O02195
PRIDE O02195
EnsemblMetazoa FBtr0079053
GeneID 33710
KEGG dme:Dmel_CG8882
UCSC CG8882-RA
CTD 33710
FlyBase FBgn0015834
eggNOG COG2319
GeneTree ENSGT00630000089849
InParanoid O02195
KO K03246
OMA KATVCAF
OrthoDB EOG7PVWPK
PhylomeDB O02195
Reactome REACT_205240
REACT_207008
REACT_207218
REACT_213100
REACT_215632
REACT_225982
SignaLink O02195
GenomeRNAi 33710
NextBio 784905
PRO PR:O02195
Proteomes UP000000803
Bgee O02195
GO GO:0016282
GO:0033290
GO:0005852
GO:0005875
GO:0003743
GO:0001731
GO:0006446
GO:0006413
Gene3D 2.130.10.10
HAMAP MF_03008
InterPro IPR027525
IPR015943
IPR001680
IPR019775
IPR017986
Pfam PF00400
SMART SM00320
SUPFAM SSF50978
PROSITE PS00678
PS50082
PS50294

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006413

translational initiation

PMID:17392269[1]

IDA: Inferred from Direct Assay

P

Figure 4 characterizes the association of Drosophila eIF3 to the 40S ribosomal subunit during normal and active translation.

complete
CACAO 4671

GO:0001731

formation of translation preinitiation complex

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

P

Seeded From UniProt

complete

GO:0003743

translation initiation factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027525

F

Seeded From UniProt

complete

GO:0003743

translation initiation factor activity

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

F

Seeded From UniProt

complete

GO:0003743

translation initiation factor activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0396

F

Seeded From UniProt

complete

GO:0003743

translation initiation factor activity

PMID:10908586[2]

ISS: Inferred from Sequence or Structural Similarity

F

Seeded From UniProt

Missing: with/from

GO:0005737

cytoplasm

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027525

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0005852

eukaryotic translation initiation factor 3 complex

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027525

C

Seeded From UniProt

complete

GO:0005852

eukaryotic translation initiation factor 3 complex

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

C

Seeded From UniProt

complete

GO:0005852

eukaryotic translation initiation factor 3 complex

PMID:10908586[2]

ISS: Inferred from Sequence or Structural Similarity

C

Seeded From UniProt

Missing: with/from

GO:0005875

microtubule associated complex

PMID:18433294[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0006412

translation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0648

P

Seeded From UniProt

complete

GO:0006413

translational initiation

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

P

Seeded From UniProt

complete

GO:0006413

translational initiation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0396

P

Seeded From UniProt

complete

GO:0006413

translational initiation

PMID:10908586[2]

ISS: Inferred from Sequence or Structural Similarity

P

Seeded From UniProt

Missing: with/from

GO:0006446

regulation of translational initiation

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

P

Seeded From UniProt

complete

GO:0016282

eukaryotic 43S preinitiation complex

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

C

Seeded From UniProt

complete

GO:0033290

eukaryotic 48S preinitiation complex

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03008

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Andersen, DS & Leevers, SJ (2007) The essential Drosophila ATP-binding cassette domain protein, pixie, binds the 40 S ribosome in an ATP-dependent manner and is required for translation initiation. J. Biol. Chem. 282 14752-60 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lasko, P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J. Cell Biol. 150 F51-6 PubMed GONUTS page
  3. Hughes, JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol. 6 e98 PubMed GONUTS page