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DROME:EI3D1
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | eIF3d1 (ECO:0000255 with HAMAP-Rule:MF_03003) (synonyms: eIF-3p66) | |
| Protein Name(s) | Eukaryotic translation initiation factor 3 subunit D-1 (ECO:0000255 with HAMAP-Rule:MF_03003)
eIF3d-1 (ECO:0000255 with HAMAP-Rule:MF_03003) Eukaryotic translation initiation factor 3 subunit 7-1 (ECO:0000255 with HAMAP-Rule:MF_03003) Eukaryotic translation initiation factor 3 subunit p66 | |
| External Links | ||
| UniProt | Q9VCK0 | |
| EMBL | AF220363 AE014297 BT023923 | |
| RefSeq | NP_524463.2 | |
| UniGene | Dm.2369 | |
| ProteinModelPortal | Q9VCK0 | |
| SMR | Q9VCK0 | |
| BioGrid | 67727 | |
| IntAct | Q9VCK0 | |
| MINT | Q9VCK0 | |
| STRING | 7227.FBpp0088565 | |
| iPTMnet | Q9VCK0 | |
| PaxDb | Q9VCK0 | |
| PRIDE | Q9VCK0 | |
| EnsemblMetazoa | FBtr0089622 | |
| GeneID | 42789 | |
| KEGG | dme:Dmel_CG10161 | |
| UCSC | CG10161-RB | |
| CTD | 42789 | |
| FlyBase | FBgn0040227 | |
| eggNOG | KOG2479 ENOG410XP1E | |
| GeneTree | ENSGT00390000002667 | |
| InParanoid | Q9VCK0 | |
| KO | K03251 | |
| OMA | DRIFHTV | |
| OrthoDB | EOG091G07IK | |
| PhylomeDB | Q9VCK0 | |
| Reactome | R-DME-156827 R-DME-72649 R-DME-72689 R-DME-72695 R-DME-72702 | |
| ChiTaRS | eIF-3p66 | |
| GenomeRNAi | 42789 | |
| PRO | PR:Q9VCK0 | |
| Proteomes | UP000000803 | |
| Bgee | FBgn0040227 | |
| ExpressionAtlas | Q9VCK0 | |
| Genevisible | Q9VCK0 | |
| GO | GO:0005829 GO:0005852 GO:0005634 GO:0003743 GO:0006446 GO:0006413 | |
| HAMAP | MF_03003 | |
| InterPro | IPR007783 | |
| PANTHER | PTHR12399 | |
| Pfam | PF05091 | |
| PIRSF | PIRSF016281 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003743 |
translation initiation factor activity |
ECO:0000315 |
F |
Depletion of eIF3d from SL2 cells reduced translation of an msl-2 reporter, while depletion of other subunits (eIF3e, eIF3h) had no effect (Figure 5DE) |
complete | |||||
|
involved_in |
GO:0006446 |
regulation of translational initiation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005852 |
eukaryotic translation initiation factor 3 complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003743 |
translation initiation factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006413 |
translational initiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000273956 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005852 |
eukaryotic translation initiation factor 3 complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0040227 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003743 |
translation initiation factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0040227 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003743 |
translation initiation factor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
Missing: with/from | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
Missing: with/from | |||
|
involved_in |
GO:0006413 |
translational initiation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
Missing: with/from | |||
|
part_of |
GO:0005852 |
eukaryotic translation initiation factor 3 complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
Missing: with/from | |||
|
enables |
GO:0003743 |
translation initiation factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005852 |
eukaryotic translation initiation factor 3 complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003743 |
translation initiation factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0002183 |
cytoplasmic translational initiation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0002191 |
cap-dependent translational initiation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001732 |
formation of cytoplasmic translation initiation complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016282 |
eukaryotic 43S preinitiation complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0033290 |
eukaryotic 48S preinitiation complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0098808 |
mRNA cap binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005852 |
eukaryotic translation initiation factor 3 complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000106267 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006412 |
translation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003743 |
translation initiation factor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006413 |
translational initiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Szostak, E et al. (2018) Hrp48 and eIF3d contribute to msl-2 mRNA translational repression. Nucleic Acids Res. PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Somma, MP et al. (2008) Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference. PLoS Genet. 4 e1000126 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Lasko, P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J. Cell Biol. 150 F51-6 PubMed GONUTS page
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