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Category:GO:0005078 ! MAP-kinase scaffold activity
name: MAP-kinase scaffold activity
namespace: molecular_function
def: "The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently." [PMID:12511654, PMID:15213240, PMID:9405336]
synonym: "MAP-kinase scaffold protein activity" EXACT []
is_a: GO:0035591 ! signaling adaptor activity
relationship: has_part: GO:0051019 ! mitogen-activated protein kinase binding
relationship: part_of: GO:0000165 ! MAPK cascade
AmiGO
<GOterm>GO:0005078</GOterm>
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