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MOUSE:KSR2
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Ksr2 (ECO:0000312 with MGI:MGI:3610315) | |
| Protein Name(s) | Kinase suppressor of Ras 2 | |
| External Links | ||
| UniProt | Q3UVC0 | |
| EMBL | AC113299 AC113303 AC114617 AK137433 | |
| UniGene | Mm.437947 | |
| ProteinModelPortal | Q3UVC0 | |
| SMR | Q3UVC0 | |
| PhosphoSite | Q3UVC0 | |
| MaxQB | Q3UVC0 | |
| PaxDb | Q3UVC0 | |
| PRIDE | Q3UVC0 | |
| UCSC | uc008zfw.2 | |
| MGI | MGI:3610315 | |
| eggNOG | KOG0193 | |
| HOGENOM | HOG000110293 | |
| HOVERGEN | HBG052293 | |
| InParanoid | Q3UVC0 | |
| PhylomeDB | Q3UVC0 | |
| NextBio | 13857732 | |
| PRO | PR:Q3UVC0 | |
| Proteomes | UP000000589 | |
| Bgee | Q3UVC0 | |
| CleanEx | MM_KSR2 | |
| Genevestigator | Q3UVC0 | |
| GO | GO:0005829 GO:0005886 GO:0005524 GO:0005078 GO:0046872 GO:0031434 GO:0004674 GO:0019722 GO:0043410 | |
| InterPro | IPR011009 IPR025561 IPR002219 IPR000719 IPR001245 IPR008271 | |
| Pfam | PF13543 PF07714 | |
| SMART | SM00109 | |
| SUPFAM | SSF56112 | |
| PROSITE | PS50011 PS00108 PS00479 PS50081 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0120162 |
positive regulation of cold-induced thermogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019722 |
calcium-mediated signaling |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:3610315 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007265 |
Ras protein signal transduction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0015402 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:3610315 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:3610315 |
C |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0043410 |
positive regulation of MAPK cascade |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0031434 |
mitogen-activated protein kinase kinase binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0019722 |
calcium-mediated signaling |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:107164 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005078 |
MAP-kinase scaffold activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Guo, L et al. (2017) Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis. Mol Metab 6 194-205 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Dougherty, MK et al. (2009) KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals. Mol. Cell 34 652-62 PubMed GONUTS page
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