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Category:GO:0004471 ! malate dehydrogenase (decarboxylating) (NAD+) activity
name: malate dehydrogenase (decarboxylating) (NAD+) activity
namespace: molecular_function
alt_id: GO:0004472
alt_id: GO:0016619
def: "Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH." [RHEA:12653]
comment: For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.38), see 'oxaloacetate decarboxylase activity ; GO:0008948'.
synonym: "'malic' enzyme" RELATED [EC:1.1.1.38, EC:1.1.1.39]
synonym: "(S)-malate:NAD+ oxidoreductase (decarboxylating)" RELATED [EC:1.1.1.39]
synonym: "(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)" RELATED [EC:1.1.1.38]
synonym: "malate dehydrogenase (decarboxylating) activity" RELATED [EC:1.1.1.39]
synonym: "malate dehydrogenase (oxaloacetate-decarboxylating) activity" EXACT []
synonym: "NAD-linked malic enzyme" RELATED [EC:1.1.1.38]
synonym: "NAD-malic enzyme activity" BROAD [EC:1.1.1.38, EC:1.1.1.39]
synonym: "NAD-specific malic enzyme" RELATED [EC:1.1.1.38, EC:1.1.1.39]
xref: EC:1.1.1.39
xref: KEGG_REACTION:R00214
xref: MetaCyc:1.1.1.39-RXN
xref: RHEA:12653
is_a: GO:0004470 ! malic enzyme activity
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
AmiGO
<GOterm>GO:0004471</GOterm>
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