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YEAST:YAP1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | YAP1 (synonyms: PAR1, PDR4, SNQ3) | |
| Protein Name(s) | AP-1-like transcription factor YAP1
Phenanthroline resistance protein PAR1 Pleiotropic drug resistance protein PDR4 | |
| External Links | ||
| UniProt | P19880 | |
| EMBL | X58693 X53830 X60780 X63268 Z49810 BK006946 | |
| PIR | S16706 | |
| RefSeq | NP_013707.1 | |
| PDB | 1SSE | |
| PDBsum | 1SSE | |
| ProteinModelPortal | P19880 | |
| SMR | P19880 | |
| BioGrid | 35163 | |
| DIP | DIP-1752N | |
| IntAct | P19880 | |
| MINT | MINT-505627 | |
| MaxQB | P19880 | |
| PaxDb | P19880 | |
| EnsemblFungi | [example_ID YML007W] | |
| GeneID | 855005 | |
| KEGG | sce:YML007W | |
| CYGD | YML007w | |
| SGD | S000004466 | |
| eggNOG | NOG72873 | |
| GeneTree | ENSGT00530000069148 | |
| HOGENOM | HOG000142347 | |
| InParanoid | P19880 | |
| KO | K09043 | |
| OMA | CSERGVV | |
| OrthoDB | EOG7GFBHK | |
| BioCyc | YEAST:G3O-32612-MONOMER | |
| EvolutionaryTrace | P19880 | |
| NextBio | 978163 | |
| Proteomes | UP000002311 | |
| Genevestigator | P19880 | |
| GO | GO:0005737 GO:0005634 GO:0043565 GO:0003700 GO:0043619 GO:0046686 GO:0042493 GO:0009408 GO:0010038 GO:0000304 GO:0006351 | |
| Gene3D | 1.10.238.100 | |
| InterPro | IPR004827 IPR013910 IPR023167 | |
| Pfam | PF00170 PF08601 | |
| SMART | SM00338 | |
| PROSITE | PS50217 PS00036 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061395 |
positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance |
ECO:0007001 |
high throughput mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1900101 |
regulation of endoplasmic reticulum unfolded protein response |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0034599) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043619 |
regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042493 |
response to drug |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010038 |
response to metal ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009408 |
response to heat |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0034599) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000304 |
response to singlet oxygen |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046686 |
response to cadmium ion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Kumar, A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev. 16 707-19 PubMed GONUTS page
- ↑ 2.0 2.1 Tkach, JM et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat. Cell Biol. 14 966-76 PubMed GONUTS page
- ↑ Haugen, AC et al. (2004) Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol. 5 R95 PubMed GONUTS page
- ↑ Maity, S et al. (2016) Oxidative Homeostasis Regulates the Response to Reductive Endoplasmic Reticulum Stress through Translation Control. Cell Rep 16 851-65 PubMed GONUTS page
- ↑ Yi, DG et al. (2016) Yap1 and Skn7 genetically interact with Rad51 in response to oxidative stress and DNA double-strand break in Saccharomyces cerevisiae. Free Radic. Biol. Med. 101 424-433 PubMed GONUTS page
- ↑ 6.0 6.1 Nguyên, DT et al. (2001) Multiple Yap1p-binding sites mediate induction of the yeast major facilitator FLR1 gene in response to drugs, oxidants, and alkylating agents. J. Biol. Chem. 276 1138-45 PubMed GONUTS page
- ↑ Lucau-Danila, A et al. (2005) Early expression of yeast genes affected by chemical stress. Mol. Cell. Biol. 25 1860-8 PubMed GONUTS page
- ↑ Wu, A et al. (1993) Yeast bZip proteins mediate pleiotropic drug and metal resistance. J. Biol. Chem. 268 18850-8 PubMed GONUTS page
- ↑ Sugiyama, K et al. (2000) The Yap1p-dependent induction of glutathione synthesis in heat shock response of Saccharomyces cerevisiae. J. Biol. Chem. 275 15535-40 PubMed GONUTS page
- ↑ 10.0 10.1 Kuge, S et al. (1997) Regulation of yAP-1 nuclear localization in response to oxidative stress. EMBO J. 16 1710-20 PubMed GONUTS page
- ↑ 11.0 11.1 Bauer, NC et al. (2013) Automated quantification of the subcellular localization of multicompartment proteins via Q-SCAn. Traffic 14 1200-8 PubMed GONUTS page
- ↑ 12.0 12.1 Wiatrowski, HA & Carlson, M (2003) Yap1 accumulates in the nucleus in response to carbon stress in Saccharomyces cerevisiae. Eukaryotic Cell 2 19-26 PubMed GONUTS page
- ↑ Brombacher, K et al. (2006) The role of Yap1p and Skn7p-mediated oxidative stress response in the defence of Saccharomyces cerevisiae against singlet oxygen. Yeast 23 741-50 PubMed GONUTS page
f
o
r
- GO:0006355 ! regulation of DNA-templated transcription
- GO:1900101 ! regulation of endoplasmic reticulum unfolded protein response
- GO:0009408 ! response to heat
- GO:0000304 ! response to singlet oxygen
- GO:0010038 ! response to metal ion
- GO:0046686 ! response to cadmium ion
- GO:0042493 ! response to drug
