GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:15575969
| Citation |
Haugen, AC, Kelley, R, Collins, JB, Tucker, CJ, Deng, C, Afshari, CA, Brown, JM, Ideker, T and Van Houten, B (2004) Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol. 5:R95 |
|---|---|
| Abstract |
Arsenic is a nonmutagenic carcinogen affecting millions of people. The cellular impact of this metalloid in Saccharomyces cerevisiae was determined by profiling global gene expression and sensitivity phenotypes. These data were then mapped to a metabolic network composed of all known biochemical reactions in yeast, as well as the yeast network of 20,985 protein-protein/protein-DNA interactions. |
| Links |
PubMed PMC545798 Online version:10.1186/gb-2004-5-12-r95 |
| Keywords |
Arsenic/toxicity; Basic-Leucine Zipper Transcription Factors; Biodegradation, Environmental; Cysteine/biosynthesis; DNA-Binding Proteins/physiology; Environmental Pollutants/toxicity; Gene Expression Profiling; Gene Expression Regulation, Fungal/drug effects; Glutathione/biosynthesis; Glutathione/metabolism; Heat-Shock Response/drug effects; Methionine/metabolism; Oxidative Stress; Phenotype; Proteasome Endopeptidase Complex/metabolism; Saccharomyces cerevisiae/drug effects; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae Proteins/genetics; Saccharomyces cerevisiae Proteins/metabolism; Saccharomyces cerevisiae Proteins/physiology; Selenium/metabolism; Sulfur/metabolism; Toxicity Tests/methods; Trans-Activators/physiology; Transcription Factors/genetics; Transcription Factors/physiology; Transcription, Genetic |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| edit table |
See also
References
See Help:References for how to manage references in GONUTS.
