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YEAST:RIF1
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | RIF1 | |
| Protein Name(s) | Telomere length regulator protein RIF1
RAP1-interacting factor 1 | |
| External Links | ||
| UniProt | P29539 | |
| EMBL | X66501 Z36144 Z36145 X76053 BK006936 | |
| PIR | S46157 | |
| RefSeq | NP_009834.4 | |
| PDB | 4BJS 4BJT | |
| PDBsum | 4BJS 4BJT | |
| ProteinModelPortal | P29539 | |
| SMR | P29539 | |
| BioGrid | 32970 | |
| DIP | DIP-801N | |
| IntAct | P29539 | |
| MINT | MINT-2780441 | |
| iPTMnet | P29539 | |
| SwissPalm | P29539 | |
| MaxQB | P29539 | |
| PeptideAtlas | P29539 | |
| EnsemblFungi | [example_ID YBR275C] | |
| GeneID | 852578 | |
| KEGG | sce:YBR275C | |
| EuPathDB | FungiDB:YBR275C | |
| SGD | S000000479 | |
| InParanoid | P29539 | |
| KO | K11118 | |
| OrthoDB | EOG7R838T | |
| BioCyc | YEAST:G3O-29196-MONOMER | |
| NextBio | 971718 | |
| PRO | PR:P29539 | |
| Proteomes | UP000002311 | |
| GO | GO:0000784 GO:0070187 GO:0042162 GO:0007049 GO:0030466 GO:0000729 GO:0006270 GO:0016233 GO:0000723 | |
| InterPro | IPR028566 IPR022031 | |
| PANTHER | PTHR22928 | |
| Pfam | PF12231 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0070198 |
protein localization to chromosome, telomeric region |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_direct_input:(UniProtKB:P32598) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006270 |
DNA replication initiation |
ECO:0000353 |
physical interaction evidence used in manual assertion |
SGD:S000002459 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006270 |
DNA replication initiation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
SGD:S000002175 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070187 |
shelterin complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042162 |
telomeric DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030466 |
chromatin silencing at silent mating-type cassette |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016233 |
telomere capping |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000784 |
nuclear chromosome, telomeric region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000729 |
DNA double-strand break processing |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0051318)|happens_during:(GO:0051319) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000723 |
telomere maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0050085 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000723 |
telomere maintenance |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1098622 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005694 |
chromosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000781 |
chromosome, telomeric region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kedziora, S et al. (2018) Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast. Nucleic Acids Res. 46 3993-4003 PubMed GONUTS page
- ↑ 2.0 2.1 Hiraga, S et al. (2014) Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex. Genes Dev. 28 372-83 PubMed GONUTS page
- ↑ Shi, T et al. (2013) Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions. Cell 153 1340-53 PubMed GONUTS page
- ↑ Sabourin, M et al. (2007) Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol. Cell 27 550-61 PubMed GONUTS page
- ↑ 5.0 5.1 Hardy, CF et al. (1992) A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation. Genes Dev. 6 801-14 PubMed GONUTS page
- ↑ Bonetti, D et al. (2010) Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres. PLoS Genet. 6 e1000966 PubMed GONUTS page
- ↑ Bourns, BD et al. (1998) Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo. Mol. Cell. Biol. 18 5600-8 PubMed GONUTS page
- ↑ Martina, M et al. (2014) Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection. EMBO Rep. 15 695-704 PubMed GONUTS page
- ↑ 9.0 9.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
