GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

YEAST:IMA1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) SRP1 (synonyms: KAP60)
Protein Name(s) Importin subunit alpha

Karyopherin subunit alpha Karyopherin-60 Serine-rich RNA polymerase I suppressor protein

External Links
UniProt Q02821
EMBL M75849
Z71465
BK006947
PIR S30884
RefSeq NP_014210.1
PDB 1BK5
1BK6
1EE4
1EE5
1UN0
1WA5
2C1T
4PVZ
4XZR
5H2W
5H2X
5T94
PDBsum 1BK5
1BK6
1EE4
1EE5
1UN0
1WA5
2C1T
4PVZ
4XZR
5H2W
5H2X
5T94
ProteinModelPortal Q02821
SMR Q02821
BioGrid 35644
DIP DIP-728N
ELM Q02821
IntAct Q02821
MINT Q02821
STRING 4932.YNL189W
iPTMnet Q02821
MaxQB Q02821
PaxDb Q02821
PRIDE Q02821
EnsemblFungi YNL189W
GeneID 855532
KEGG sce:YNL189W
EuPathDB FungiDB:YNL189W
SGD S000005133
GeneTree ENSGT00760000119094
HOGENOM HOG000167616
InParanoid Q02821
OMA PYAITIE
OrthoDB EOG092C1PRY
BioCyc YEAST:G3O-33200-MONOMER
EvolutionaryTrace Q02821
PRO PR:Q02821
Proteomes UP000002311
GO GO:0005737
GO:0005829
GO:0042564
GO:0005643
GO:0005654
GO:0005634
GO:0048471
GO:0043234
GO:0097718
GO:0061608
GO:0008139
GO:0008565
GO:0006607
GO:0031144
GO:0006606
GO:0006612
Gene3D 1.20.5.690
1.25.10.10
InterPro IPR011989
IPR016024
IPR032413
IPR000225
IPR002652
IPR036975
IPR024931
Pfam PF00514
PF16186
PF01749
PIRSF PIRSF005673
SMART SM00185
SUPFAM SSF48371
PROSITE PS50176
PS51214

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0042564

NLS-dependent protein nuclear import complex

PMID:19141610[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:11914276[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

PMID:15602554[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0042564

NLS-dependent protein nuclear import complex

PMID:12065587[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0097718

disordered domain specific binding

PMID:12065587[4]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P32499

F

Seeded From UniProt

complete

involved_in

GO:0031144

proteasome localization

PMID:25274630[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008565

protein transporter activity

PMID:7622450[6]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006612

protein targeting to membrane

PMID:16929305[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006607

NLS-bearing protein import into nucleus

PMID:19141610[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_direct_input:(UniProtKB:P13259)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:10725229[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:10725229[8]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0044877

protein-containing complex binding

PMID:19046973[9]

ECO:0000314

direct assay evidence used in manual assertion

F

has_input:(GO:0000176)

Seeded From UniProt

complete

enables

GO:0008565

protein transporter activity

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1100836
PANTHER:PTN000593662
SGD:S000005133
WB:WBGene00002072

F

Seeded From UniProt

complete

enables

GO:0008139

nuclear localization sequence binding

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000593662
RGD:735064

F

Seeded From UniProt

complete

involved_in

GO:0006607

NLS-bearing protein import into nucleus

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000593662
PomBase:SPBC1604.08c
RGD:735064
UniProtKB:Q8IAW0

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000593662
TAIR:locus:2083313
TAIR:locus:2132238
TAIR:locus:2143423
TAIR:locus:2195351
TAIR:locus:505006475
UniProtKB:O15131
UniProtKB:P52294

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000593662
PomBase:SPBC1604.08c
UniProtKB:P52294
WB:WBGene00002072

C

Seeded From UniProt

complete

part_of

GO:0005643

nuclear pore

PMID:21873635[10]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000593662
PomBase:SPBC1604.08c
WB:WBGene00002072

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024931
InterPro:IPR036975

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024931
InterPro:IPR036975

C

Seeded From UniProt

complete

involved_in

GO:0006606

protein import into nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002652
InterPro:IPR024931
InterPro:IPR036975

P

Seeded From UniProt

complete

enables

GO:0008565

protein transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR036975

F

Seeded From UniProt

complete

enables

GO:0061608

nuclear import signal receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002652
InterPro:IPR024931

F

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0198

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 MacKinnon, MA et al. (2009) The Kap60-Kap95 karyopherin complex directly regulates phosphatidylcholine synthesis. J. Biol. Chem. 284 7376-84 PubMed GONUTS page
  2. ↑ Kumar, A et al. (2002) Subcellular localization of the yeast proteome. Genes Dev. 16 707-19 PubMed GONUTS page
  3. ↑ Matsuura, Y & Stewart, M (2004) Structural basis for the assembly of a nuclear export complex. Nature 432 872-7 PubMed GONUTS page
  4. ↑ 4.0 4.1 Denning, DP et al. (2002) The Saccharomyces cerevisiae nucleoporin Nup2p is a natively unfolded protein. J. Biol. Chem. 277 33447-55 PubMed GONUTS page
  5. ↑ Chen, L & Madura, K (2014) Yeast importin-α (Srp1) performs distinct roles in the import of nuclear proteins and in targeting proteasomes to the nucleus. J. Biol. Chem. 289 32339-52 PubMed GONUTS page
  6. ↑ Enenkel, C et al. (1995) Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J. Biol. Chem. 270 16499-502 PubMed GONUTS page
  7. ↑ King, MC et al. (2006) Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature 442 1003-7 PubMed GONUTS page
  8. ↑ 8.0 8.1 Hood, JK et al. (2000) Nup2p is located on the nuclear side of the nuclear pore complex and coordinates Srp1p/importin-alpha export. J. Cell. Sci. 113 ( Pt 8) 1471-80 PubMed GONUTS page
  9. ↑ Synowsky, SA et al. (2009) Comparative multiplexed mass spectrometric analyses of endogenously expressed yeast nuclear and cytoplasmic exosomes. J. Mol. Biol. 385 1300-13 PubMed GONUTS page
  10. ↑ 10.0 10.1 10.2 10.3 10.4 10.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=YEAST:IMA1&oldid=5945012"