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XENLA:STA31

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Species (Taxon ID) Xenopus laevis (African clawed frog). (8355)
Gene Name(s) stat3.1 (synonyms: stat3 (ECO:0000303 with PMID:10642787[1]))
Protein Name(s) Signal transducer and activator of transcription 3.1

Protein Stat3 (ECO:0000250 with UniProtKB:P40763) Xstat3 (ECO:0000303 with PMID:10642787[1])

External Links
UniProt Q9PVX8
EMBL AB017701
BC169718
BC169720
RefSeq NP_001090202.1
UniGene Xl.57141
ProteinModelPortal Q9PVX8
SMR Q9PVX8
PRIDE Q9PVX8
GeneID 779100
KEGG xla:779100
CTD 779100
Xenbase XB-GENE-865436
KO K04692
GO GO:0005737
GO:0005634
GO:0005886
GO:0005509
GO:0003677
GO:0046983
GO:0019901
GO:0043565
GO:0003700
GO:0004871
GO:0042755
GO:0001754
GO:0042593
GO:0060397
GO:0001707
GO:0014033
GO:0045893
GO:0006357
GO:0019953
GO:0001659
GO:0006351
Gene3D 1.10.238.10
1.10.532.10
1.20.1050.20
2.60.40.630
3.30.505.10
InterPro IPR011992
IPR008967
IPR000980
IPR001217
IPR013800
IPR015988
IPR013801
IPR012345
IPR013799
PANTHER PTHR11801
Pfam PF00017
PF01017
PF02864
PF02865
SMART SM00252
SM00964
SUPFAM SSF47655
SSF48092
SSF49417
SSF55550
PROSITE PS50001

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0060397

growth hormone receptor signaling pathway via JAK-STAT

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

enables

GO:0046983

protein dimerization activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

F

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

PMID:10642787[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:10642787[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0042755

eating behavior

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

involved_in

GO:0042593

glucose homeostasis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

involved_in

GO:0019953

sexual reproduction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

PMID:15004007[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q8QGV6

F

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

F

Seeded From UniProt

complete

involved_in

GO:0014033

neural crest cell differentiation

PMID:18710660[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006357

regulation of transcription by RNA polymerase II

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

F

Seeded From UniProt

complete

involved_in

GO:0001754

eye photoreceptor cell differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

involved_in

GO:0001707

mesoderm formation

PMID:15004007[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0001659

temperature homeostasis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P42227

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013801

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217
InterPro:IPR008967

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217
InterPro:IPR008967
InterPro:IPR013799
InterPro:IPR013800
InterPro:IPR015988

P

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001217
InterPro:IPR013799
InterPro:IPR013800
InterPro:IPR015988

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Nishinakamura, R et al. (1999) Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4. Dev. Biol. 216 481-90 PubMed GONUTS page
  2. 2.0 2.1 Ohkawara, B et al. (2004) Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction. Genes Dev. 18 381-6 PubMed GONUTS page
  3. Nichane, M et al. (2008) Hairy2 functions through both DNA-binding and non DNA-binding mechanisms at the neural plate border in Xenopus. Dev. Biol. 322 368-80 PubMed GONUTS page