User:Zdebstep

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	DEIRD:O83028	2013-03-26 12:25:31 CDT	GO:0070895 negative regulation of transposon integration (P)	PMID:23461641	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3B. Shows in vivo TnpB down regulation of transposon integration, in the presence of TnpA.	challenge
updatedbyinstructor	DEIRA:Q9RWB3	2013-04-11 20:55:21 CDT	GO:0036297 interstrand cross-link repair (P)	PMID:23239186	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 5e, 5f. YeaZ null mutants show sensitivity to cisplatin and MMC. Cisplatin and MMC cause DNA cross links, which will then inhibit replication. Implying that the YeaZ gene is required for repair of DNA cross links.	challenge
updatedbyinstructor	ECOLX:E2QE90	2013-04-11 21:38:03 CDT	GO:0002949 tRNA threonylcarbamoyladenosine modification (P)	PMID:21183954	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3C. YgjD is required for t6a modification of tRNAs. E. coli was grown with the inducible arabinose promotor, instead of the ygjD promotor. This strain, with the arabinose promotor, was then grown in the presence and absence of arabinose. In the presence of arabinose the t6a/A ratio was approximately 40 times higher then in the absence of arabinose.	challenge
updatedbyinstructor	DEIRD:D0EM60	2013-04-12 08:20:39 CDT	GO:0008409 5'-3' exonuclease activity (F)	PMID:19944654	ECO:0000314 direct assay evidence used in manual assertion	Fig 7 or 8	challenge
unacceptable	?	2013-04-12 22:02:35 CDT	GO:1900192 positive regulation of single-species biofilm formation (Figure 1 illustrates that gltC mutants show decreased biofilm formation in comparison to the wild type.)	PMID:23562858	IMP: Inferred from Mutant Phenotype		challenge
updatedbyinstructor	DEIRA:RECA	2013-04-14 15:49:50 CDT	GO:0006302 double-strand break repair (P)	PMID:20090937	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4 shows that gamma radiation sensitivity increases in recA mutants. Figure 6 illustrates that DNA repair in recA mutants started becoming visible at 24 hours.	challenge
updatedbyinstructor	DEIRA:RECF	2013-04-14 15:58:05 CDT	GO:0006302 double-strand break repair (P)	PMID:20090937	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4B. recF mutants have a higher sensitivity to gamma radiation. In Figure 6A DNA repair of the recF mutant is shown by gel electrophoresis.	challenge
updatedbyinstructor	DEIRA:Q9RW50	2013-04-14 16:01:32 CDT	GO:0006302 double-strand break repair (P)	PMID:20090937	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4B illustrates that doses of gamma radiation causes decreased cell survival in recO mutants. Figure 6A shows reassembly of DNA fragments around 24 hours after irradiation.	challenge
updatedbyinstructor	DEIRA:RECR	2013-04-14 16:04:56 CDT	GO:0006302 double-strand break repair (P)	PMID:20090937	ECO:0000315 mutant phenotype evidence used in manual assertion	In Figure 4B cells with recR mutants show an increased sensitivity to gamma radiation. Figure 6A illustrates that there is repair of DNA fragments 24 hours after irradiation.	challenge

acceptable:1
unacceptable:1
requires_changes:0
flagged:0

Annotations challenged by Zdebstep

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Zdebstep, Team Hot Pockets	ECOLX:E2QE90	GO:0002949 - tRNA threonylcarbamoyladenosine modification (P)	PMID:21183954	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 4 fixed by Zdebstep
updatedbyinstructor	Zdebstep, Team Hot Pockets	DEIRD:D0EM60	GO:0008409 - 5'-3' exonuclease activity (F)	PMID:19944654	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 3 fixed by Zdebstep

2 annotations fixed by Zdebstep

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