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User:Koenigl1

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SUPER BOWL (Round 5)

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
requireschangesPSEPA:Q7WST12012-04-14 23:32:31 CDTGO:0070988 demethylation (P)PMID:15090517ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7 shows that analysis of desA mutants is essential to the O demethylation activity of syringate.

challenge
acceptableSYNY3:HGGT2012-04-15 00:11:03 CDTGO:0010189 vitamin E biosynthetic process (P)PMID:11418103ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2 shows significant differences of Vitamin E concentrations, with a major reduction of product in the mutant strain as compared to wild type. Further tests show that Vitamin E concentrations were the only substance effected showing its relation to vitamin E biosynthesis.


challenge
requireschangesSTRAD:Q537402012-04-15 00:51:30 CDTGO:0043638 puromycin biosynthetic process (P)PMID:15556612ECO:0000314 direct assay evidence used in manual assertion

Figure 4 shows an assay of the Pac enzyme with pur6 products. Pac is shown to be highly specific interactign with only puromycin carbon backbones. Based on the interaction of pur6 and the Pac enzyme, and the specificity of the enzyme that pur6 is involved in the puromycin synthesis.

challenge
requireschangesARATH:LUT12012-04-15 10:18:03 CDTGO:0016117 carotenoid biosynthetic process (P)PMID:14709673ECO:0000315 mutant phenotype evidence used in manual assertion

Comparison of mutant strains versus wild type show that LUT1 exclusively encodes for ε-hydroxylase activity in photosynthetic tissues and carries this function out as part of carotenoid synthesis.

challenge
requireschangesTOBAC:Q38Q862012-04-15 11:20:32 CDTGO:0032451 demethylase activity (F)PMID:16192354ECO:0000315 mutant phenotype evidence used in manual assertion

Analysis of mutant strains along with comparison to similar genes within organism point to CYP82E4v1 being responsible for demethylation of nicotine.

challenge

acceptable:1
unacceptable:0
requires_changes:4
flagged:0

Annotations challenged by Koenigl1

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
requireschangesLabbeben,
Team ppGpp 3 Times Fast
MYXXD:Q1D7Q3GO:0003677 - DNA binding (F)PMID:1539954ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1

0 annotations fixed by Koenigl1


MSU Internal

No annotations for this user (yet.)
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My Annotations

Annotations challenged by Koenigl1

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
requireschangesLabbeben,
Team ppGpp 3 Times Fast
MYXXD:Q1D7Q3GO:0003677 - DNA binding (F)PMID:1539954ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1

0 annotations fixed by Koenigl1