User:Kaycee.Bartels

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	BPMD2:VG66	2016-04-07 02:05:05 CDT	GO:0004112 cyclic-nucleotide phosphodiesterase activity (F)	PMID:25307893	ECO:0000314 direct assay evidence used in manual assertion	Figure 2 shows phosphoesterase activity of the gene product. Figure 3 compares activity to mutated genes and shows that phosphoesterase activity goes down for mutated genes.	challenge
unacceptable	9CAUD:Q2Z146	2016-04-11 03:41:53 CDT	GO:0016465 chaperonin ATPase complex (C)	PMID:22787217	ECO:0000314 direct assay evidence used in manual assertion	Figure 7 shows ADP and ATP binding to recombinant gp146 Figure 8 B compares gp146 and gp188* with and without 3mM of ATP and shows that gp188* in the presence of gp146 and ATP is not affected.	challenge
acceptable	BPMD2:THYX	2016-04-20 22:11:41 CDT	GO:0050797 thymidylate synthase (FAD) activity (F)	PMID:18248423	ECO:0000314 direct assay evidence used in manual assertion	Figure 2 Shows the characterization of gp48 thymidylate synthase (ThyX) activity. Figure 2b shows that it is a flavoprotein because it contains bound FAD. It was also said to be detectable soon after the lytic phase of growth had commenced.	challenge
unacceptable	BPMD2:VG50	2016-04-20 22:23:32 CDT	GO:0008998 ribonucleoside-triphosphate reductase activity (F)	PMID:18248423	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 showed the characterization of ribonucleotide reductase activity of gp50. Figure 3b showed the enzyme could reduce of ATP to dATP. In the presence of various nucleotides, only dGTP stimulated reduction of ATP (Figure 3c). It was stated on the bottom of page 69 at the bottom of the left-hand column, that the enzyme was only found to reduce only triphosphate and not diphosphate.	challenge

acceptable:2
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Kaycee.Bartels

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
unacceptable	Barlowrm, Team TRUMP2016	HUMAN:HPRT	GO:0000100 - S-methylmethionine transmembrane transporter activity (F)	PMID:17662107	ECO:0000250 sequence similarity evidence used in manual assertion	challenge	C: 2
updatedbyinstructor	Barlowrm, Team TRUMP2016	BACSU:TYSY1	GO:0004799 - thymidylate synthase activity (F)	PMID:9778348	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 4
unacceptable	JefferyPowell, Team T1	BPN15:O64356	GO:0043433 - negative regulation of DNA-binding transcription factor activity (P)	PMID:17158670	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
unacceptable	JefferyPowell, Team T1	9PAST:W0Q5Y1	GO:0043433 - negative regulation of DNA-binding transcription factor activity (P)	PMID:17158670	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1
updatedbyinstructor	Flounlackerkm, Team DirtyChubi	BPSPP:Q38152	GO:0006268 - DNA unwinding involved in DNA replication (P)	PMID:18157148	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1

0 annotations fixed by Kaycee.Bartels

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