BACSU:TYSY1

Species (Taxon ID)	Bacillus subtilis (strain 168). (224308)
Gene Name(s)	thyA1 (ECO:0000255 with HAMAP-Rule:MF_00008)
Protein Name(s)	Thymidylate synthase 1 (ECO:0000255 with HAMAP-Rule:MF_00008) TS 1 (ECO:0000255 with HAMAP-Rule:MF_00008) TSase 1 (ECO:0000255 with HAMAP-Rule:MF_00008) Thymidylate synthase A (ECO:0000255 with HAMAP-Rule:MF_00008) TS A (ECO:0000255 with HAMAP-Rule:MF_00008) TSase A (ECO:0000255 with HAMAP-Rule:MF_00008)
External Links
UniProt	P0CI79
EMBL	X78560 AL009126 AF004102
PIR	I40494
RefSeq	NP_389651.1 WP_003244896.1
PDB	1B02 1BKO 1BKP 1BSF 1BSP
PDBsum	1B02 1BKO 1BKP 1BSF 1BSP
ProteinModelPortal	P0CI79
SMR	P0CI79
STRING	224308.Bsubs1_010100009726
PaxDb	P0CI79
EnsemblBacteria	CAB13652
GeneID	939555
KEGG	bsu:BSU17680
PATRIC	18975359
eggNOG	ENOG4105C0V COG0207
HOGENOM	HOG000257898
InParanoid	P0CI79
KO	K00560
OMA	KELLWIW
OrthoDB	EOG6K6V53
PhylomeDB	P0CI79
BRENDA	2.1.1.45
SABIO-RK	P0CI79
UniPathway	UPA00575
EvolutionaryTrace	P0CI79
Proteomes	UP000001570
GO	GO:0005737 GO:0004799 GO:0006231 GO:0006235
Gene3D	3.30.572.10
HAMAP	MF_00008
InterPro	IPR023451 IPR000398 IPR020940
Pfam	PF00303
PRINTS	PR00108
SUPFAM	SSF55831
TIGRFAMs	TIGR03284
PROSITE	PS00091

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004799	thymidylate synthase activity	PMID:9778348	ECO:0000314			F		"Activity assays indicate that bsTS-A has a significantly higher specific activity (SA ≈ 22 units/mg) than either E. coli TS (SA ∼13.5 units/mg) or L. casei TS (SA ≈ 6 units/mg) when measured using the identical materials and instruments." Data not shown.	complete CACAO 11501
enables	GO:0004799	thymidylate synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000398 InterPro:IPR020940	F		Seeded From UniProt	complete
involved_in	GO:0006231	dTMP biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000398 InterPro:IPR020940	P		Seeded From UniProt	complete
enables	GO:0004799	thymidylate synthase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.1.1.45	F		Seeded From UniProt	complete
enables	GO:0004799	thymidylate synthase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000074698	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000074698	C		Seeded From UniProt	complete
involved_in	GO:0006231	dTMP biosynthetic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000074698	P		Seeded From UniProt	complete
involved_in	GO:0032259	methylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0489	P		Seeded From UniProt	complete
involved_in	GO:0009165	nucleotide biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0545	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0008168	methyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0489	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0006235	dTTP biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00575	P		Seeded From UniProt	complete
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References

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