User:Hjack

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
unacceptable	MOUSE:ENY2	2016-04-11 10:47:08 CDT	GO:0006006 glucose metabolic process (P)	PMID:22649445	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3(d) - Glucose metabolism as measured by an MTT assay Increased after ENY2 knockdown.	challenge
unacceptable	MOUSE:ENY2	2016-04-11 10:58:25 CDT	GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus (P)	PMID:22649445	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3(e) - Insulin secretion increases in response to Tolbutamide stimulus after ENY2 supression.	challenge
unacceptable	MOUSE:ENY2	2016-04-11 11:06:34 CDT	GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus (P)	PMID:22649445	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4(c) - Insulin secretion increased in response to stimulation with 50nmol/l exendin-4 and 10μmol/1 forskolin.	challenge
unacceptable	PANTR:DX39B	2016-04-15 09:50:18 CDT	GO:0051095 regulation of helicase activity (P)	PMID:21637952	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig 3(a) - UAP56 appear to become unstable when Plk1 was most abundant. Fig 3(b) - depletion of Plk1 dramatically increased the stability of UAP56.	challenge
updatedbyinstructor	MOUSE:PLK1	2016-04-15 09:06:53 CDT	GO:0004672 protein kinase activity (F)	PMID:21637952	ECO:0000314 direct assay evidence used in manual assertion	Fig 2(a) - Wild type Plk1 phosphorylates UAP56.	challenge
updatedbyinstructor	MOUSE:PLK1	2016-04-15 09:18:23 CDT	GO:0006468 protein phosphorylation (P)	PMID:21637952	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig 2(b) - Phosphorylation of UAP56 is dependent upon levels of Plk1.	challenge

acceptable:0
unacceptable:4
requires_changes:0
flagged:0

Annotations challenged by Hjack

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Hjack

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