PANTR:DX39B

Species (Taxon ID)	Pan troglodytes (Chimpanzee). (9598)
Gene Name(s)	DDX39B (synonyms: BAT1, UAP56)
Protein Name(s)	Spliceosome RNA helicase DDX39B 56 kDa U2AF65-associated protein DEAD box protein UAP56
External Links
UniProt	P60024
EMBL	AB054536 BA000041 AB210169 AB210170
RefSeq	NP_001107635.1
UniGene	Ptr.5754
ProteinModelPortal	P60024
SMR	P60024
STRING	9598.ENSPTRP00000054521
PaxDb	P60024
PRIDE	P60024
GeneID	463180
KEGG	ptr:463180
CTD	7919
eggNOG	KOG0329 COG0513
HOVERGEN	HBG107334
InParanoid	P60024
KO	K12812
NextBio	20842239
Proteomes	UP000002277
GO	GO:0005737 GO:0016607 GO:0005681 GO:0005524 GO:0004004 GO:0003723 GO:0006974 GO:0006406 GO:0000398 GO:2000002 GO:0032786 GO:0010468 GO:0010501
Gene3D	3.40.50.300
InterPro	IPR011545 IPR014001 IPR001650 IPR027417 IPR014014
Pfam	PF00270 PF00271
SMART	SM00487 SM00490
SUPFAM	SSF52540
PROSITE	PS51192 PS51194 PS51195

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0051095	regulation of helicase activity	PMID:21637952	ECO:0000315			P		Fig 3(a) - UAP56 appear to become unstable when Plk1 was most abundant. Fig 3(b) - depletion of Plk1 dramatically increased the stability of UAP56.	complete CACAO 11747
involved_in	GO:2000002	negative regulation of DNA damage checkpoint	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q13838	P		Seeded From UniProt	complete
involved_in	GO:0032786	positive regulation of DNA-templated transcription, elongation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q13838	P		Seeded From UniProt	complete
involved_in	GO:2000002	negative regulation of DNA damage checkpoint	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
involved_in	GO:0046784	viral mRNA export from host cell nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
enables	GO:0043008	ATP-dependent protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	F		Seeded From UniProt	complete
involved_in	GO:0032786	positive regulation of DNA-templated transcription, elongation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
enables	GO:0030621	U4 snRNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	F		Seeded From UniProt	complete
enables	GO:0017070	U6 snRNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	F		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
involved_in	GO:0010501	RNA secondary structure unwinding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
involved_in	GO:0008380	RNA splicing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
enables	GO:0008186	RNA-dependent ATPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	F		Seeded From UniProt	complete
involved_in	GO:0006406	mRNA export from nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
part_of	GO:0005688	U6 snRNP	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
part_of	GO:0005687	U4 snRNP	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
part_of	GO:0005681	spliceosomal complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
enables	GO:0004004	ATP-dependent RNA helicase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	F		Seeded From UniProt	complete
involved_in	GO:0000398	mRNA splicing, via spliceosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
part_of	GO:0000346	transcription export complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
involved_in	GO:0000245	spliceosomal complex assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13838 ensembl:ENSP00000416269	P		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A024RCM3 ensembl:ENSP00000416269	C		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011545	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011545	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
involved_in	GO:0006397	mRNA processing	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0507	P		Seeded From UniProt	complete
involved_in	GO:0051028	mRNA transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0509	P		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
involved_in	GO:0008380	RNA splicing	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0508	P		Seeded From UniProt	complete
part_of	GO:0005681	spliceosomal complex	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0747	C		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0004386	helicase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0347	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0186	C		Seeded From UniProt	complete
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References

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