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User:Curtis.baker4500

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My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableHUMAN:P2RX72012-10-04 15:49:58 CDTGO:0010628 positive regulation of gene expression (P)PMID:22898868ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4-P2X7R expression causes overexpression of the key glycolytic enzymes G3PDH and PFK.

challenge
acceptableHUMAN:P2RX72012-10-17 18:14:24 CDTGO:0045821 positive regulation of glycolysis (P)PMID:22898868ECO:0000315 mutant phenotype evidence used in manual assertion

From figure 1 it shows that P2X7R expression stimulates cell metabolism

challenge
unacceptableMOUSE:GSK3B2012-11-15 07:45:43 CSTPMID:2831860ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3- GSKB gene deletion reduced renal AQP2 levels

challenge
unacceptableSTRCO:Q9X7U22012-11-16 15:43:22 CSTGO:0043581 mycelium development (P)PMID:19682261ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7- shows that chpB is not essential for formation of the fimbriae as these structures were still produced in the ΔchpABCDH mutant strain.

challenge
unacceptableSTRCO:Q9AD932012-11-16 15:45:10 CSTGO:0043581 mycelium development (P)PMID:19682261ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7- shows that chpC is not essential for formation of the fimbriae as these structures were still produced in the ΔchpABCDH mutant strain.

challenge
unacceptableHUMAN:VDR2012-11-17 19:36:48 CSTGO:0045670 regulation of osteoclast differentiation (P)PMID:23149425ECO:0000314 direct assay evidence used in manual assertion

Fig. 1. 1,25(OH)2D3 inhibits osteoclastogenesis in the human osteoclast precursors from normal peripheral blood (PB)

challenge
unacceptableMOUSE:AS3MT2012-11-18 08:25:07 CSTGO:0050922 negative regulation of chemotaxis (P)PMID:23152186ECO:0000314 direct assay evidence used in manual assertion

Fig 2. As(III) causes concentration dependent inhibition of hMSC differentiation to adipocytes.

challenge

acceptable:2
unacceptable:5
requires_changes:0
flagged:0

Annotations challenged by Curtis.baker4500

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history

0 annotations fixed by Curtis.baker4500