User:Ayuan

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
requireschanges	PHAND:O74696	2013-03-06 11:16:48 CST	GO:0052014 catabolism by symbiont of host protein (P)	PMID:10796020	ECO:0000314 direct assay evidence used in manual assertion	Fig. 5 shows SNP1 could degrade structural hydroxyproline-rich protein into small fragments.	challenge
updatedbyinstructor	PSETT:VKT1	2013-03-06 11:25:33 CST	GO:0004867 serine-type endopeptidase inhibitor activity (F)	PMID:19236611	ECO:0000314 direct assay evidence used in manual assertion	Table 1: textilinin-1 shows inhibition activity of plasmin and trypsin(low Ki values)	challenge
updatedbyinstructor	PSETT:VKT1	2013-03-15 14:54:02 CDT	GO:0035899 negative regulation of blood coagulation in other organism (P)	PMID:19236611	ECO:0000314 direct assay evidence used in manual assertion	Fig. 1D: Textilinin-1 negatively regulated blood loss in a mouse tail vein model	challenge
updatedbyinstructor	BOMTE:VKT	2013-03-17 16:12:22 CDT	GO:0004867 serine-type endopeptidase inhibitor activity (F)	PMID:23164714	ECO:0000314 direct assay evidence used in manual assertion	Figure 2B. Bt-KTI inhibits the enzymatic activity of trypsin	challenge
updatedbyinstructor	BOMTE:VKT	2013-03-17 16:12:22 CDT	GO:0051918 negative regulation of fibrinolysis (P)	PMID:23164714	ECO:0000314 direct assay evidence used in manual assertion	Fig 3: Bt-KTI inhibits plasmin formation	challenge
acceptable	BOVIN:BPT1	2013-03-17 17:17:46 CDT	GO:0070495 negative regulation of thrombin receptor signaling pathway (P)	PMID:1378406	ECO:0000314 direct assay evidence used in manual assertion	Fig. 4: Aprotinin inhibits the ability of thrombin to induce a fibrin clot. The fibrinogen concentration was contant at curve a while the clotting time increased from curve b to e with the presence of aprotinin	challenge
acceptable	BOVIN:BPT1	2013-03-25 14:04:15 CDT	GO:0090331 negative regulation of platelet aggregation (P)	PMID:1378406	ECO:0000314 direct assay evidence used in manual assertion	Fig. 5 shows the aggregation of human platelets was reduced by increasing concentration of aprotinin. Curve a was the control(without the presence of aprotinin)	challenge

acceptable:2
unacceptable:0
requires_changes:1
flagged:0

Annotations challenged by Ayuan

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

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