PSETT:VKT1

Species (Taxon ID)	Pseudonaja textilis textilis (Eastern brown snake). (169397)
Gene Name(s)	No Information Provided.
Protein Name(s)	Kunitz-type serine protease inhibitor textilinin-1 Txln-1
External Links
UniProt	Q90WA1
EMBL	AF402324
PDB	3BYB 3D65 3UIR
PDBsum	3BYB 3D65 3UIR
ProteinModelPortal	Q90WA1
SMR	Q90WA1
MEROPS	I02.052
EvolutionaryTrace	Q90WA1
GO	GO:0005576 GO:0004867 GO:0035899 GO:0010951
Gene3D	4.10.410.10
InterPro	IPR002223 IPR020901
Pfam	PF00014
PRINTS	PR00759
SMART	SM00131
SUPFAM	SSF57362
PROSITE	PS00280 PS50279

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004867	serine-type endopeptidase inhibitor activity	PMID:19236611	ECO:0000314			F		Table 1: textilinin-1 shows inhibition activity of plasmin and trypsin(low Ki values)	complete CACAO 6833
	GO:0035899	negative regulation of blood coagulation in other organism	PMID:19236611	ECO:0000314			P		Fig. 1D: Textilinin-1 negatively regulated blood loss in a mouse tail vein model	complete CACAO 6934
involved_in	GO:0035899	negative regulation of blood coagulation in other organism	PMID:19236611	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004867	serine-type endopeptidase inhibitor activity	PMID:19236611	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0090729	P		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004867	P		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004867	P		Seeded From UniProt	complete
involved_in	GO:0010951	negative regulation of endopeptidase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004867	P		Seeded From UniProt	complete
enables	GO:0004867	serine-type endopeptidase inhibitor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002223 InterPro:IPR036880	F		Seeded From UniProt	complete
enables	GO:0090729	toxin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0800	F		Seeded From UniProt	complete
involved_in	GO:0010466	negative regulation of peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	P		Seeded From UniProt	complete
enables	GO:0004867	serine-type endopeptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0722	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0030414	peptidase inhibitor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0646	F		Seeded From UniProt	complete
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References

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