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BOMTE:VKT

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Species (Taxon ID) Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris). (30195)
Gene Name(s) No Information Provided.
Protein Name(s) Kunitz-type serine protease inhibitor Bt-KTI
External Links
UniProt D8KY58
EMBL EU860215
JX273645
JX273646
RefSeq XP_003396032.1
GeneID 100631053
GO GO:0005576
GO:0004867
GO:0010951
GO:0051918
Gene3D 4.10.410.10
InterPro IPR002223
IPR020901
Pfam PF00014
PRINTS PR00759
SMART SM00131
SUPFAM SSF57362
PROSITE PS00280
PS50279

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004867

serine-type endopeptidase inhibitor activity

PMID:23164714[1]

ECO:0000314

F

Figure 2B. Bt-KTI inhibits the enzymatic activity of trypsin

complete
CACAO 6981

GO:0051918

negative regulation of fibrinolysis

PMID:23164714[1]

ECO:0000314

P

Fig 3: Bt-KTI inhibits plasmin formation

complete
CACAO 6982

involved_in

GO:0051918

negative regulation of fibrinolysis

PMID:23164714[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

PMID:23164714[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

involved_in

GO:0010951

negative regulation of endopeptidase activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004867

P

Seeded From UniProt

complete

involved_in

GO:0010951

negative regulation of endopeptidase activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004867

P

Seeded From UniProt

complete

involved_in

GO:0010951

negative regulation of endopeptidase activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004867

P

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002223
InterPro:IPR036880

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0030414

peptidase inhibitor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0646

F

Seeded From UniProt

complete

involved_in

GO:0010466

negative regulation of peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0646

P

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0722

F

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Qiu, Y et al. (2013) Molecular cloning and antifibrinolytic activity of a serine protease inhibitor from bumblebee (Bombus terrestris) venom. Toxicon 63 1-6 PubMed GONUTS page