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Cacao

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GO:0009405pathogenesisPMID:8516329IDA: Inferred from Direct Assay P
This annotation made on page: HELPX:Q9JP55
By: Sarah.budde (group Team A-Squared) on 2014-03-02 10:34:52 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengePierluis,
MichSt14A 43
2014-04-08 11:03:09 CDT

All of these figures are depicting different features of cagA using different methods, so an IDA evidence code is not sufficient to cover everything. Additionally, there is no provided evidence to support the GO term provided (GO:0016337 - cell-cell adhesion (P))

0
ChallengeRdesai525,
Team Texas Aggies
2014-03-25 19:49:19 CDT

There are multiple figures described and IDA evidence code alone is not appropriate. Also Figure 2 and 3 are schematics and are not allowed in CACAO. Also all four figures are not good enough to get an annotation. Figure 1 says that the cag-A antigen is 128 kDa, but it does not support with any further information like its function, or localization in the cell. Figure 4 only proves that cag-A antigen is homologous in two different strains types- cytotoxic and non-cytotoxic.

0
Private
Assessment
Suzialeksander2014-05-13 15:34:18 CDTYou need to be an instructor to view these notes.Unacceptable
Public
Assessment
Suzialeksander2014-04-16 16:10:09 CDT

Pierluis made comments but didn't suggest any changes or point out previously unnoticed mistakes.

Requires Changes
Private
Assessment
Briddle242014-04-01 20:21:48 CDTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
DanielRenfro2014-03-25 19:49:19 CDT

This annotation has been flagged because it has been edited since last assessment ||GO:0009405||pathogenesis||PMID:8516329||IDA: Inferred from Direct Assay||||P||Figure 1 shows the expression and size of the CagA Antigen. Figure 2 shows the gene map of cagA by the use of clones. Figure 3 shows the nucleotide sequence of cagA as well as indicates the ribosomal binding sites and termination sites. Figure 4 shows the southern blot of the chromosomal DNA of a cytotoxic H. pylori strain and a non-cytotoxic strain of H. pylori.||complete

Flagged
Private
Assessment
Briddle242014-03-04 19:11:22 CSTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original