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HELPX:Q9JP55
Contents
| Species (Taxon ID) | Helicobacter pylori (Campylobacter pylori). (210) | |
| Gene Name(s) | cagA (ECO:0000313 with EMBL:AAF43620.1) | |
| Protein Name(s) | CagA (ECO:0000313 with EMBL:AAN86014.1)
Cytotoxin associated protein CagA (ECO:0000313 with EMBL:AAF43620.1) | |
| External Links | ||
| UniProt | Q9JP55 | |
| EMBL | AF198480 AY162446 AY162450 AY162453 AY169293 AY169294 AY169295 AY169296 AY169297 AB056955 AB056956 AB056960 AB056962 AB056963 AB056964 AB056965 AB056966 AB056967 AB056968 AB056970 AB056977 AB056978 AB056980 AB056983 AB056986 AB056989 AB056991 AB056992 AB056993 AB056994 AB056997 AB056998 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0070062 |
extracellular vesicular exosome |
ECO:0000314 |
C |
Figure 8 shows immunogold analysis of CagA, demonstrating localization to bacterial vesicle surface. |
complete | |||||
| GO:0016337 |
cell-cell adhesion |
ECO:0000314 |
P |
Figure 4 shows the southern blot of the chromosomal DNA of a cytotoxic H. pylori strain and a non-cytotoxic strain of H. pylori. |
complete | |||||
| GO:0098865 |
modification by symbiont of host bicellular tight junctions |
ECO:0000315 |
P |
Figure 5. SEM Analysis CagA positive H. pylori cells induced morphological changes to human gastric cells junctions. |
complete | |||||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0098865 |
modification by symbiont of host bicellular tight junctions |
ECO:0000315 |
P |
Figure 5. SEM Analysis CagA positive H. pylori cells induced morphological changes to human gastric cells junctions. |
complete | |||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Olofsson, A et al. (2010) Biochemical and functional characterization of Helicobacter pylori vesicles. Mol. Microbiol. 77 1539-55 PubMed GONUTS page
- ↑ Covacci, A et al. (1993) Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc. Natl. Acad. Sci. U.S.A. 90 5791-5 PubMed GONUTS page
- ↑ 3.0 3.1 Song, X et al. () H. pylori-encoded CagA disrupts tight junctions and induces invasiveness of AGS gastric carcinoma cells via Cdx2-dependent targeting of Claudin-2. Cell. Immunol. 286 22-30 PubMed GONUTS page
