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GO:0031264PMID:7536190IMP: Inferred from Mutant Phenotype
This annotation made on page: HUMAN:FADD
By: Astephens2 (group Team Bacon Pancakes) on 2014-01-30 20:50:26 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeAmstutzc,
MichSt14A 1
2014-04-13 14:34:01 CDT

To show that this FADD protein has a death domain to death domain interaction with Fas, a figure should be indicated in the notes along with an explanation as to why. Figure 6 shows that FADD with a V-->N point mutation in the critical residue for the domain no longer binds to Fas. However normal FADD protein can still bind. This suggests the V121 is responsible for interaction of FADD and Fas.

0
ChallengeNicoleNThorndal,
Team Designer Genes
2014-03-09 19:56:19 CDT

You must provide evidence in your notes. Where/what figure or experiment from your paper did you find this information to support your hypothesis.

Designer genes

0
ChallengeDruelas,
Team BGOW
2014-02-06 15:47:12 CST

Evidence code needs to be a direct assay.

0
Private
Assessment
Suzialeksander2014-05-07 16:20:43 CDTYou need to be an instructor to view these notes.Unacceptable
Private
Assessment
JimHu2014-04-19 18:18:20 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2014-04-13 14:34:01 CDT

This annotation has been flagged because it has been edited since last assessment ||GO:0031264||death-inducing signaling complex||PMID:7536190||IMP: Inferred from Mutant Phenotype||||C||Northern and Sequence Analyses||complete

Flagged
Private
Assessment
Suzialeksander2014-03-21 16:46:15 CDTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
DanielRenfro2014-03-09 19:56:19 CDT

This annotation has been flagged because it has been edited since last assessment ||GO:0031264||death-inducing signaling complex||PMID:7536190||IMP: Inferred from Mutant Phenotype||||C||Northern and Sequence Analyses||complete

Flagged
Private
Assessment
Suzialeksander2014-02-18 12:14:20 CSTYou need to be an instructor to view these notes.Requires Changes
Notes