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GO:0046597negative regulation of viral entry into host cellPMID:23358889IDA: Inferred from Direct Assay P
This annotation made on page: HUMAN:IFM2
By: Zstielper (group Team Everything Burrito) on 2013-02-10 13:25:01 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeDeradeza,
Team Team TATAboxxx
2013-04-16 12:21:39 CDT

The Evidence Code should be IMP. IDA makes more sense to me overall, but IMP may also work.

0
ChallengeMessanyn,
Team The Knockouts
2013-04-07 16:27:57 CDT

Figure 3 shows that the use of IFITM/IFN treated cells suppresses the formation of syncytia. Figure 4 shows that cell to cell fusion via JSRV Env is prevented when IFITM proteins are present in the cell. Both results were found by fluorescence microscopy. Figure 5 plots the % fusion seen by each type of protein (IFITM1,2,3). Based on this figure, IFITM1 and 3 show a lower rate of cell to cell fusion in parts A-D, but only IFITM shows a significantly lower fusion rate in part E.

0
Public
Assessment
JimHu2013-04-16 20:21:03 CDT

IDA is used for ectopic overexpression to examine the normal function of a gene product. http://www.geneontology.org/GO.evidence.shtml#ida

Acceptable
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2013-04-16 12:21:39 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Bmcintosh2013-04-09 13:03:53 CDTYou need to be an instructor to view these notes.Requires Changes
Evidence
Public
Assessment
DanielRenfro2013-04-07 16:27:57 CDT

This annotation has been flagged because it has been edited since last assessment

Flagged
Private
Assessment
Bmcintosh2013-02-19 20:37:49 CSTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original