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Cacao

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GO:0071236cellular response to antibioticPMID:8981985IDA: Inferred from Direct Assay P
This annotation made on page: ENTFC:VANX
By: Brice.Sondrol (group Team Spartan) on 2016-02-23 15:45:58 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeHeidi.Larson.1,
Team Grapes of Staph
2016-04-19 01:50:51 CDT

Also in the with/from category, it looks like the enzyme encoded by VanH is important. It looks like VanHAX are all part of an operon that is regulated by a VanR-VanS two-component system. The beginning mentions that the VanHAX operon encodes the enzymes that confer the antibiotic resistance.

0
ChallengeHeidi.Larson.1,
Team Grapes of Staph
2016-04-19 01:41:15 CDT

Because the paper references several different genes, I would use the evidence code IGI: Inferred from Genetic Interaction. In the with/from category, I would add the proteins encoded by VanS, VanR, and VanA.

1
ChallengeHeidi.Larson.1,
Team Grapes of Staph
2016-03-28 22:24:15 CDT

I would take a look at this Go term GO:0009870. It relates to antibiotic resistance.

0
Private
Assessment
Suzialeksander2016-06-13 13:50:49 CDTYou need to be an instructor to view these notes.Unacceptable
Private
Assessment
Suzialeksander2016-05-03 16:22:00 CDTYou need to be an instructor to view these notes.Requires Changes
Public
Assessment
DanielRenfro2016-04-19 01:50:51 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Public
Assessment
DanielRenfro2016-04-19 01:41:15 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Suzialeksander2016-04-11 12:52:26 CDTYou need to be an instructor to view these notes.Requires Changes
Publication
Qualifier
Go term
Evidence
With/From
Private
Assessment
Suzialeksander2016-04-11 12:48:06 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Private
Assessment
Suzialeksander2016-04-04 00:20:00 CDTYou need to be an instructor to view these notes.Flagged
Public
Assessment
DanielRenfro2016-03-29 16:17:19 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0010628 positive regulation of gene expression PMID:8981985 IDA: Inferred from Direct Assay P Fig. 4 shows production of VanX can be induced by different vancomycin concentrations. Expression of VanX is positively regulated in presence of vancomycin. complete
CACAO 11321
on ENTFC:VANX
Flagged
Public
Assessment
DanielRenfro2016-03-28 22:24:16 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Public
Assessment
JimHu2016-03-08 14:33:03 CST

Response to terms are not allowed.

I marked the paper as acceptable because there are functional inferences that are allowable in it. But because there were multiple annotations submitted to this paper, and because this one is associated with VanX, fixing this might work best with another paper.

Requires Changes
Publication
Go term
Private
Assessment
Suzialeksander2016-03-07 13:30:44 CSTYou need to be an instructor to view these notes.Unacceptable
Publication
Go term
Private
Assessment
Suzialeksander2016-03-07 13:29:34 CSTYou need to be an instructor to view these notes.Unacceptable
Publication
Qualifier
Go term