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User:Brice.Sondrol

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CACAO Spring 2016

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableENTFC:VANX2016-02-23 15:45:58 CSTGO:0010628 positive regulation of gene expression (P)PMID:8981985ECO:0000314 direct assay evidence used in manual assertion

Fig. 4 shows production of VanX can be induced by different vancomycin concentrations. Expression of VanX is positively regulated in presence of vancomycin.

challenge
unacceptableENTFC:I6ZX042016-04-13 10:18:38 CDTGO:1900232 negative regulation of single-species biofilm formation on inanimate substrate (P)PMID:22876178ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7B indicates that a biofilm is formed on polystyrene with an asrR knockout mutant, whereas the parental strain produces no biofilm. As a result, asrR negatively regulates biofilm formation on an inanimate substrate.

challenge
unacceptableENTFC:I6ZX042016-04-14 01:17:49 CDTGO:0034115 negative regulation of heterotypic cell-cell adhesion (P)PMID:22876178ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7C indicates that asrR knockout mutants are more adherent to HT-29 cells than cells from the parental strain. As a result, asrR negatively regulates heterotypic cell-cell adhesion.

challenge

acceptable:0
unacceptable:3
requires_changes:0
flagged:0

Annotations challenged by Brice.Sondrol

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableLiza.M.Stremick,
Team The Jackson 5
STRPY:Q5R2E0GO:0008219 - cell death (P)PMID:26838722ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 3

0 annotations fixed by Brice.Sondrol

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