PMID:18578884

Citation	Denton, AM, Wu, J, Townsend, MK, Sule, P and Prüss, BM (2008) Relating gene expression data on two-component systems to functional annotations in Escherichia coli. BMC Bioinformatics 9:294
Abstract	Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionally, this has been done in two consecutive steps. The first step identifies important genes through clustering or statistical techniques, while the second step assigns biological functions to the identified groups. Recently, techniques have been developed that identify such relationships in a single step.
Links	PubMed PMC2478693 Online version:10.1186/1471-2105-9-294
Keywords	Adaptation, Biological/genetics; Algorithms; Artificial Intelligence; Chi-Square Distribution; Databases, Genetic; Escherichia coli/genetics; Escherichia coli/metabolism; Gene Expression/physiology; Gene Expression Profiling/methods; Gene Expression Regulation, Bacterial; Neural Networks (Computer); Oligonucleotide Array Sequence Analysis/methods; Oligonucleotide Array Sequence Analysis/statistics & numerical data; Pattern Recognition, Automated; Protein Kinases/genetics; Protein Kinases/metabolism; Signal Transduction; Transcription Factors/genetics; Transcription Factors/metabolism
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Annotations

Gene product	Qualifier	GO Term	Evidence Code	with/from	Aspect	Extension	Notes	Status
ECOLI:BASS		GO:0009242: colanic acid biosynthetic process	ECO:0000317:	PMID:12366850	P		Tables 4 and 5 from 18578884 (Denton et al., 2008) describe the computational analysis of a data set from Oshima et al (12366850). Many of the genes of the colanic acid operon (wca) are regulated by this protein.	complete CACAO 2122
ECOLI:NTRB		GO:0009242: colanic acid biosynthetic process	ECO:0000317:	PMID:12366850	P		Tables 4 and 5 from 18578884 (Denton et al., 2008) describe the computational analysis of a data set from Oshima et al (12366850). Many of the genes of the colanic acid operon (wca) are regulated by this protein.	complete CACAO 2124
ECOLI:UVRY		GO:0009242: colanic acid biosynthetic process	ECO:0000317:	PMID:12366850	P		Tables 4 and 5 from 18578884 (Denton et al., 2008) describe the computational analysis of a data set from Oshima et al (12366850). Many of the genes of the colanic acid operon (wca) are regulated by this protein.	complete CACAO 2123
ECOLI:UVRY		GO:0042710: biofilm formation	ECO:0000315:		P		Fig. 8, quantitative biofilm assay	complete CACAO 1948
ECOLI:NTRC		GO:0042710: biofilm formation	ECO:0000315:		P		Fig. 8, quantitative biofilm assay	complete CACAO 1955

References

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