ECOLI:NTRB

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	glnL (synonyms: glnR, ntrB)
Protein Name(s)	Nitrogen regulation protein NR(II)
External Links
UniProt	P0AFB5
EMBL	X05173 L19201 U00096 AP009048 K02176
PIR	A30377
RefSeq	NP_418305.1 YP_491581.1
PDB	1R62
PDBsum	1R62
ProteinModelPortal	P0AFB5
SMR	P0AFB5
DIP	DIP-9784N
IntAct	P0AFB5
STRING	511145.b3869
PaxDb	P0AFB5
EnsemblBacteria	AAC76866 BAE77440
GeneID	12933635 948360
KEGG	ecj:Y75_p3317 eco:b3869
PATRIC	32123241
EchoBASE	EB0382
EcoGene	EG10387
eggNOG	COG3852
HOGENOM	HOG000262169
InParanoid	P0AFB5
KO	K07708
OMA	HNFARLH
OrthoDB	EOG6G4VQG
PhylomeDB	P0AFB5
BioCyc	EcoCyc:PROTEIN-NRII ECOL316407:JW3840-MONOMER
EvolutionaryTrace	P0AFB5
PRO	PR:P0AFB5
Proteomes	UP000000318 UP000000625
Genevestigator	P0AFB5
GO	GO:0005622 GO:0016020 GO:0005524 GO:0042802 GO:0004721 GO:0000155 GO:0016311 GO:0009399 GO:0000160 GO:0046777 GO:0051171 GO:0006355 GO:0023014
Gene3D	1.10.287.130 3.30.565.10
InterPro	IPR003661 IPR003594 IPR000014 IPR013767 IPR004358 IPR005467 IPR009082
Pfam	PF02518 PF00512 PF00989
PRINTS	PR00344
SMART	SM00387 SM00388 SM00091
SUPFAM	SSF47384 SSF55785 SSF55874
PROSITE	PS50109 PS50112

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0042802	identical protein binding	PMID:24561554^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P0AFB5	F	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:15150219^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P0AFB5	F	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:12838411^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P0AFB5	F	Seeded From UniProt	complete
involved_in	GO:0051171	regulation of nitrogen compound metabolic process	PMID:6113591^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0046777	protein autophosphorylation	PMID:8226644^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0023014	signal transduction by protein phosphorylation	PMID:2874557^[6]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0004721	phosphoprotein phosphatase activity	PMID:2874557^[6]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
	GO:0009242	colanic acid biosynthetic process	PMID:18578884^[7]	ECO:0000317		PMID:12366850^[8]	P	Tables 4 and 5 from 18578884 (Denton et al., 2008) describe the computational analysis of a data set from Oshima et al (12366850). Many of the genes of the colanic acid operon (wca) are regulated by this protein.	complete CACAO 2124
enables	GO:0000155	phosphorelay sensor kinase activity	PMID:2874557^[6]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0006470	protein dephosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004721	P	Seeded From UniProt	complete
involved_in	GO:0018106	peptidyl-histidine phosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004673	P	Seeded From UniProt	complete
enables	GO:0000155	phosphorelay sensor kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003661 InterPro:IPR036097	F	Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013767	P	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003661 InterPro:IPR036097	P	Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004358	P	Seeded From UniProt	complete
enables	GO:0016772	transferase activity, transferring phosphorus-containing groups	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004358	F	Seeded From UniProt	complete
enables	GO:0004673	protein histidine kinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.13.3	F	Seeded From UniProt	complete
involved_in	GO:0009399	nitrogen fixation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0535	P	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0902	P	Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
↑ Burillo, S et al. (2004) Interactions between the nitrogen signal transduction protein PII and N-acetyl glutamate kinase in organisms that perform oxygenic photosynthesis. J. Bacteriol. 186 3346-54 PubMed GONUTS page
↑ Salinas, P & Contreras, A (2003) Identification and analysis of Escherichia coli proteins that interact with the histidine kinase NtrB in a yeast two-hybrid system. Mol. Genet. Genomics 269 574-81 PubMed GONUTS page
↑ McFarland, N et al. (1981) Nitrogen regulatory locus "glnR" of enteric bacteria is composed of cistrons ntrB and ntrC: identification of their protein products. Proc. Natl. Acad. Sci. U.S.A. 78 2135-9 PubMed GONUTS page
↑ Ninfa, EG et al. (1993) Mechanism of autophosphorylation of Escherichia coli nitrogen regulator II (NRII or NtrB): trans-phosphorylation between subunits. J. Bacteriol. 175 7024-32 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Ninfa, AJ & Magasanik, B (1986) Covalent modification of the glnG product, NRI, by the glnL product, NRII, regulates the transcription of the glnALG operon in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 83 5909-13 PubMed GONUTS page
↑ Denton, AM et al. (2008) Relating gene expression data on two-component systems to functional annotations in Escherichia coli. BMC Bioinformatics 9 294 PubMed GONUTS page
↑ Oshima, T et al. (2002) Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12. Mol. Microbiol. 46 281-91 PubMed GONUTS page

[PMID:24561554-1] Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page

[PMID:15150219-2] Burillo, S et al. (2004) Interactions between the nitrogen signal transduction protein PII and N-acetyl glutamate kinase in organisms that perform oxygenic photosynthesis. J. Bacteriol. 186 3346-54 PubMed GONUTS page

[PMID:12838411-3] Salinas, P & Contreras, A (2003) Identification and analysis of Escherichia coli proteins that interact with the histidine kinase NtrB in a yeast two-hybrid system. Mol. Genet. Genomics 269 574-81 PubMed GONUTS page

[PMID:6113591-4] McFarland, N et al. (1981) Nitrogen regulatory locus "glnR" of enteric bacteria is composed of cistrons ntrB and ntrC: identification of their protein products. Proc. Natl. Acad. Sci. U.S.A. 78 2135-9 PubMed GONUTS page

[PMID:8226644-5] Ninfa, EG et al. (1993) Mechanism of autophosphorylation of Escherichia coli nitrogen regulator II (NRII or NtrB): trans-phosphorylation between subunits. J. Bacteriol. 175 7024-32 PubMed GONUTS page

[PMID:2874557-6] 6.0 ^6.1 ^6.2 Ninfa, AJ & Magasanik, B (1986) Covalent modification of the glnG product, NRI, by the glnL product, NRII, regulates the transcription of the glnALG operon in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 83 5909-13 PubMed GONUTS page

[PMID:18578884-7] Denton, AM et al. (2008) Relating gene expression data on two-component systems to functional annotations in Escherichia coli. BMC Bioinformatics 9 294 PubMed GONUTS page

[PMID:12366850-8] Oshima, T et al. (2002) Transcriptome analysis of all two-component regulatory system mutants of Escherichia coli K-12. Mol. Microbiol. 46 281-91 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

ECOLI:NTRB

Contents

Annotations

Notes

References

a

b

c

e

g

h

i

k

n

o

p

r

s

t

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools