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HUMAN:LHX6
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | LHX6 (synonyms: LHX6.1) | |
| Protein Name(s) | LIM/homeobox protein Lhx6
LIM homeobox protein 6 LIM/homeobox protein Lhx6.1 | |
| External Links | ||
| UniProt | Q9UPM6 | |
| EMBL | AB031041 AB031042 AK126982 AK289827 AK297175 AK299709 AK313808 AL162424 AL162424 AL162424 AL162424 CH471090 CH471090 AL136570 BC103936 BC103937 | |
| CCDS | CCDS56583.1 CCDS56584.1 CCDS59144.1 CCDS6837.2 CCDS6838.2 | |
| PIR | T46907 | |
| RefSeq | NP_001229262.1 NP_001229263.1 NP_001229264.1 NP_055183.2 NP_954629.2 | |
| UniGene | Hs.103137 | |
| ProteinModelPortal | Q9UPM6 | |
| SMR | Q9UPM6 | |
| BioGrid | 117692 | |
| MINT | MINT-4718974 | |
| STRING | 9606.ENSP00000377854 | |
| DMDM | 90185239 | |
| PaxDb | Q9UPM6 | |
| PRIDE | Q9UPM6 | |
| DNASU | 26468 | |
| Ensembl | ENST00000340587 ENST00000373754 ENST00000373755 ENST00000394319 ENST00000541397 ENST00000559895 | |
| GeneID | 26468 | |
| KEGG | hsa:26468 | |
| UCSC | uc004blx.4 uc004bly.4 uc010mvw.3 uc022bmx.1 | |
| CTD | 26468 | |
| GeneCards | GC09M124964 | |
| HGNC | HGNC:21735 | |
| HPA | HPA047854 | |
| MIM | 608215 | |
| neXtProt | NX_Q9UPM6 | |
| PharmGKB | PA134949308 | |
| eggNOG | NOG264882 | |
| GeneTree | ENSGT00760000118921 | |
| HOGENOM | HOG000038965 | |
| HOVERGEN | HBG006261 | |
| InParanoid | Q9UPM6 | |
| KO | K09375 | |
| OMA | LSEDIHY | |
| OrthoDB | EOG744T9J | |
| PhylomeDB | Q9UPM6 | |
| TreeFam | TF315442 | |
| ChiTaRS | LHX6 | |
| GeneWiki | LHX6 | |
| GenomeRNAi | 26468 | |
| NextBio | 48705 | |
| PRO | PR:Q9UPM6 | |
| Proteomes | UP000005640 | |
| Bgee | Q9UPM6 | |
| CleanEx | HS_LHX6 | |
| ExpressionAtlas | Q9UPM6 | |
| Genevestigator | Q9UPM6 | |
| GO | GO:0005634 GO:0043565 GO:0003700 GO:0008270 GO:0048469 GO:0021853 GO:0021799 GO:0021800 GO:0021877 GO:0006351 | |
| Gene3D | 1.10.10.60 2.10.110.10 | |
| InterPro | IPR017970 IPR001356 IPR009057 IPR001781 | |
| Pfam | PF00046 PF00412 | |
| SMART | SM00389 SM00132 | |
| SUPFAM | SSF46689 | |
| PROSITE | PS00027 PS50071 PS00478 PS50023 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000255 |
match to sequence model evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048469 |
cell maturation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0021853 |
cerebral cortex GABAergic interneuron migration |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0021800 |
cerebral cortex tangential migration |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0021799 |
cerebral cortex radially oriented cell migration |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0267978 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030182 |
neuron differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002023 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0021884 |
forebrain neuron development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1096343 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0267978 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1100513 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000977 |
RNA polymerase II regulatory region sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0267978 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007399 |
nervous system development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Vaquerizas, JM et al. (2009) A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10 252-63 PubMed GONUTS page
- ↑ Kimura, N et al. (1999) A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains. J. Biochem. 126 180-7 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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