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HUMAN:C1QBP
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | C1QBP (synonyms: GC1QBP, HABP1, SF2P32) | |
Protein Name(s) | Complement component 1 Q subcomponent-binding protein, mitochondrial
ASF/SF2-associated protein p32 Glycoprotein gC1qBP C1qBP Hyaluronan-binding protein 1 Mitochondrial matrix protein p32 gC1q-R protein p33 | |
External Links | ||
UniProt | Q07021 | |
EMBL | L04636 X75913 AF338439 BT019898 BT019899 DQ372108 BC000435 BC013731 M69039 AF275902 | |
CCDS | CCDS11071.1 | |
PIR | JT0762 | |
RefSeq | NP_001203.1 | |
UniGene | Hs.555866 | |
PDB | 1P32 3RPX | |
PDBsum | 1P32 3RPX | |
ProteinModelPortal | Q07021 | |
SMR | Q07021 | |
BioGrid | 107169 | |
DIP | DIP-31164N | |
IntAct | Q07021 | |
MINT | MINT-246803 | |
STRING | 9606.ENSP00000225698 | |
DrugBank | DB08818 | |
TCDB | 9.B.103.1.1 | |
PhosphoSite | Q07021 | |
DMDM | 730772 | |
DOSAC-COBS-2DPAGE | Q07021 | |
OGP | Q07021 | |
MaxQB | Q07021 | |
PaxDb | Q07021 | |
PRIDE | Q07021 | |
DNASU | 708 | |
Ensembl | ENST00000225698 | |
GeneID | 708 | |
KEGG | hsa:708 | |
UCSC | uc002gby.1 | |
CTD | 708 | |
GeneCards | GC17M005336 | |
HGNC | HGNC:1243 | |
HPA | HPA026483 | |
MIM | 601269 | |
neXtProt | NX_Q07021 | |
PharmGKB | PA25624 | |
eggNOG | NOG295722 | |
GeneTree | ENSGT00390000018406 | |
HOGENOM | HOG000046272 | |
HOVERGEN | HBG000914 | |
InParanoid | Q07021 | |
KO | K15414 | |
OMA | CACGCGC | |
OrthoDB | EOG7MH0ZQ | |
PhylomeDB | Q07021 | |
TreeFam | TF315160 | |
Reactome | REACT_326 | |
ChiTaRS | C1QBP | |
EvolutionaryTrace | Q07021 | |
GeneWiki | C1QBP | |
GenomeRNAi | 708 | |
NextBio | 2880 | |
PMAP-CutDB | Q07021 | |
PRO | PR:Q07021 | |
Proteomes | UP000005640 | |
Bgee | Q07021 | |
CleanEx | HS_C1QBP | |
ExpressionAtlas | Q07021 | |
Genevestigator | Q07021 | |
GO | GO:0009986 GO:0005737 GO:0005829 GO:0005615 GO:0016020 GO:0005759 GO:0005739 GO:0005730 GO:0005634 GO:0005886 GO:0031690 GO:0001849 GO:0005540 GO:0030984 GO:0097177 GO:0003729 GO:0003714 GO:0008134 GO:0006915 GO:0007596 GO:0007597 GO:0006958 GO:0006955 GO:0045087 GO:0042256 GO:0006397 GO:0050687 GO:0032689 GO:0032695 GO:0039534 GO:0048025 GO:0039536 GO:0000122 GO:0014065 GO:0043065 GO:0045785 GO:2000510 GO:0070131 GO:0090023 GO:0051897 GO:1900026 GO:1901165 GO:0030449 GO:0008380 GO:0006351 GO:0016032 | |
Gene3D | 3.10.280.10 | |
InterPro | IPR003428 | |
Pfam | PF02330 | |
SUPFAM | SSF54529 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0005739 |
mitochondrion |
ECO:0000314 |
C |
Figure 1 in lymphoma cells. |
complete | |||||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000510 |
positive regulation of dendritic cell chemotaxis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1901165 |
positive regulation of trophoblast cell migration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1900026 |
positive regulation of substrate adhesion-dependent cell spreading |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0097177 |
mitochondrial ribosome binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0090023 |
positive regulation of neutrophil chemotaxis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
GO:0048025 |
negative regulation of mRNA splicing, via spliceosome |
ECO:0000315 |
P |
p32 assists in immune system response modulation, apoptotic regulation and expression in addition to regulating pre-mRNA splicing functions. |
complete | |||||
involved_in |
GO:0070131 |
positive regulation of mitochondrial translation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
GO:0005759 |
mitochondrial matrix |
ECO:0000314 |
C |
Figure 3 and Table II help illustrate how p32 is found in the mitochondrial matrix. On the basis of recovery of fumarase activity in the mitoplast fraction, the amount of p32 in mitoplasts accounted for about 102% p32 in intact mitochondria. Complement component 1 Q subcomponent-binding protein, mitochondrial Human |
complete | |||||
involved_in |
GO:0051897 |
positive regulation of protein kinase B signaling |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050687 |
negative regulation of defense response to virus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048025 |
negative regulation of mRNA splicing, via spliceosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045785 |
positive regulation of cell adhesion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043065 |
positive regulation of apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042256 |
mature ribosome assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039536 |
negative regulation of RIG-I signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039534 |
negative regulation of MDA-5 signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032695 |
negative regulation of interleukin-12 production |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032695 |
negative regulation of interleukin-12 production |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032689 |
negative regulation of interferon-gamma production |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0031690 |
adrenergic receptor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0030984 |
kininogen binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030449 |
regulation of complement activation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0014065 |
phosphatidylinositol 3-kinase signaling |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0009986 |
cell surface |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005540 |
hyaluronic acid binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003729 |
mRNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0001849 |
complement component C1q binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0097177 |
mitochondrial ribosome binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1194505 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0070131 |
positive regulation of mitochondrial translation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1194505 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048025 |
negative regulation of mRNA splicing, via spliceosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042256 |
mature ribosome assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1194505 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0030984 |
kininogen binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030449 |
regulation of complement activation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0009986 |
cell surface |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0008494 |
translation activator activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088828 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0034259 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005540 |
hyaluronic acid binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003729 |
mRNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1194505 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003714 |
transcription corepressor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0001849 |
complement component C1q binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000088834 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0098982 |
GABA-ergic synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0098793 |
presynapse |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0048786 |
presynaptic active zone |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0031690 |
adrenergic receptor binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0001849 |
complement component C1q binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O35796 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006955 |
immune response |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
PMID:8195709[14] |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
involved_in |
GO:0007597 |
blood coagulation, intrinsic pathway |
Reactome:R-HSA-140837 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002250 |
adaptive immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045087 |
innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008380 |
RNA splicing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002376 |
immune system process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042254 |
ribosome biogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006958 |
complement activation, classical pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006397 |
mRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005759 |
mitochondrial matrix |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005730 |
nucleolus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Soltys, BJ et al. (2000) Localization of P32 protein (gC1q-R) in mitochondria and at specific extramitochondrial locations in normal tissues. Histochem. Cell Biol. 114 245-55 PubMed GONUTS page
- ↑ Vegh, Z et al. (2006) Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR. Mol. Immunol. 43 1402-7 PubMed GONUTS page
- ↑ 3.0 3.1 Agostinis, C et al. (2010) An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development. J. Immunol. 185 4420-9 PubMed GONUTS page
- ↑ Feng, X et al. (2002) Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading. J. Immunol. 168 2441-8 PubMed GONUTS page
- ↑ Leigh, LE et al. (1998) C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms. Biochem. J. 330 ( Pt 1) 247-54 PubMed GONUTS page
- ↑ 6.0 6.1 Petersen-Mahrt, SK et al. (1999) The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation. EMBO J. 18 1014-24 PubMed GONUTS page
- ↑ Muta, T et al. (1997) p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation. J. Biol. Chem. 272 24363-70 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Waggoner, SN et al. (2005) gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway. J. Immunol. 175 4706-14 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Xu, L et al. (2009) Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria. Proc. Natl. Acad. Sci. U.S.A. 106 1530-5 PubMed GONUTS page
- ↑ Sunayama, J et al. (2004) Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32. Cell Death Differ. 11 771-81 PubMed GONUTS page
- ↑ Yoshikawa, H et al. (2011) Splicing factor 2-associated protein p32 participates in ribosome biogenesis by regulating the binding of Nop52 and fibrillarin to preribosome particles. Mol. Cell Proteomics 10 M110.006148 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Waggoner, SN et al. (2007) HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production. J. Leukoc. Biol. 82 1407-19 PubMed GONUTS page
- ↑ 13.0 13.1 Herwald, H et al. (1996) Isolation and characterization of the kininogen-binding protein p33 from endothelial cells. Identity with the gC1q receptor. J. Biol. Chem. 271 13040-7 PubMed GONUTS page
- ↑ 14.0 14.1 14.2 14.3 Ghebrehiwet, B et al. (1994) Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q. J. Exp. Med. 179 1809-21 PubMed GONUTS page
- ↑ Mahdi, F et al. (2001) Expression and colocalization of cytokeratin 1 and urokinase plasminogen activator receptor on endothelial cells. Blood 97 2342-50 PubMed GONUTS page
- ↑ 16.0 16.1 16.2 16.3 16.4 Chattopadhyay, C et al. (2004) Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro. Nucleic Acids Res. 32 3632-41 PubMed GONUTS page
- ↑ Deb, TB & Datta, K (1996) Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32, a protein co-purified with splicing factor SF2. Hyaluronic acid-binding protein as P-32 protein, co-purified with splicing factor SF2. J. Biol. Chem. 271 2206-12 PubMed GONUTS page
- ↑ 18.00 18.01 18.02 18.03 18.04 18.05 18.06 18.07 18.08 18.09 18.10 18.11 18.12 18.13 18.14 18.15 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
a
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i
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- GO:0039534 ! negative regulation of MDA-5 signaling pathway
- GO:0050687 ! negative regulation of defense response to virus
- GO:0032695 ! negative regulation of interleukin-12 production
- GO:0000122 ! negative regulation of transcription by RNA polymerase II
- GO:0048025 ! negative regulation of mRNA splicing, via spliceosome
- GO:0032689 ! negative regulation of type II interferon production
- GO:0039536 ! negative regulation of RIG-I signaling pathway
- GO:0005730 ! nucleolus
- GO:0005634 ! nucleus
p
- GO:0005886 ! plasma membrane
- GO:0045785 ! positive regulation of cell adhesion
- GO:0070131 ! positive regulation of mitochondrial translation
- GO:0090023 ! positive regulation of neutrophil chemotaxis
- GO:0043065 ! positive regulation of apoptotic process
- GO:1900026 ! positive regulation of substrate adhesion-dependent cell spreading
- GO:1901165 ! positive regulation of trophoblast cell migration
- GO:0051897 ! positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
- GO:2000510 ! positive regulation of dendritic cell chemotaxis
- GO:0098793 ! presynapse
- GO:0048786 ! presynaptic active zone
- Primates
- GO:0005080 ! protein kinase C binding
r
t