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DICDI:RTOA

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Species (Taxon ID) Dictyostelium discoideum (Slime mold). (44689)
Gene Name(s) rtoA
Protein Name(s) Protein rtoA

Ratio-A

External Links
UniProt P54681
EMBL U48298
AAFI02000007
RefSeq XP_645420.1
PaxDb P54681
EnsemblProtists [example_ID DDB0185120]
GeneID 8618200
KEGG ddi:DDB_G0271916
dictyBase DDB_G0271916
OMA ITIINAQ
PRO PR:P54681
Proteomes UP000002195
UP000002195
GO GO:0005737
GO:0031210
GO:0006874
GO:0031154
GO:0048388
GO:0006887
GO:0006972
GO:0061025
GO:0045595
GO:0006885
GO:0009408
GO:0006970
GO:0006979
GO:0030587
GO:0006906

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

acts_upstream_of_or_within

GO:0009408

response to heat

PMID:21288957[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0061025

membrane fusion

PMID:10747962[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

NOT|acts_upstream_of_or_within

GO:0051726

regulation of cell cycle

PMID:8951083[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048388

endosomal lumen acidification

PMID:11719559[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045595

regulation of cell differentiation

PMID:8951083[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0031210

phosphatidylcholine binding

PMID:11719559[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031154

culmination involved in sorocarp development

PMID:11719559[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031154

culmination involved in sorocarp development

PMID:8951083[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030587

sorocarp development

PMID:8643519[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006979

response to oxidative stress

PMID:12771188[6]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006972

hyperosmotic response

PMID:17517120[7]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006970

response to osmotic stress

PMID:10747962[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006906

vesicle fusion

PMID:15679845[8]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006906

vesicle fusion

PMID:10747962[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006887

exocytosis

PMID:10747962[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006885

regulation of pH

PMID:10747962[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006874

cellular calcium ion homeostasis

PMID:11330860[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:10747962[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

NOT|enables

GO:0005509

calcium ion binding

PMID:10747962[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Pakes, NK et al. (2011) Bio-electrospraying and aerodynamically assisted bio-jetting the model eukaryotic Dictyostelium discoideum: assessing stress and developmental competency post treatment. J R Soc Interface 8 1185-91 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Brazill, DT et al. (2000) A protein containing a serine-rich domain with vesicle fusing properties mediates cell cycle-dependent cytosolic pH regulation. J. Biol. Chem. 275 19231-40 PubMed GONUTS page
  3. 3.0 3.1 3.2 Wood, SA et al. (1996) RtoA links initial cell type choice to the cell cycle in Dictyostelium. Development 122 3677-85 PubMed GONUTS page
  4. 4.0 4.1 4.2 Brazill, DT et al. (2001) ABC transporters required for endocytosis and endosomal pH regulation in Dictyostelium. J. Cell. Sci. 114 3923-32 PubMed GONUTS page
  5. Spann, TP et al. (1996) Mutagenesis and gene identification in Dictyostelium by shotgun antisense. Proc. Natl. Acad. Sci. U.S.A. 93 5003-7 PubMed GONUTS page
  6. Araki, T et al. (2003) A STAT-regulated, stress-induced signalling pathway in Dictyostelium. J. Cell. Sci. 116 2907-15 PubMed GONUTS page
  7. Na, J et al. (2007) STATc is a key regulator of the transcriptional response to hyperosmotic shock. BMC Genomics 8 123 PubMed GONUTS page
  8. Li, Z et al. (2005) Dictyostelium discoideum strains lacking the RtoA protein are defective for maturation of the Legionella pneumophila replication vacuole. Cell. Microbiol. 7 431-42 PubMed GONUTS page
  9. Azhar, M et al. (2001) Cell cycle phase, cellular Ca2+ and development in Dictyostelium discoideum. Int. J. Dev. Biol. 45 405-14 PubMed GONUTS page