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DICDI:PAXB

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Species (Taxon ID) Dictyostelium discoideum (Slime mold). (44689)
Gene Name(s) paxB
Protein Name(s) Paxillin-B
External Links
UniProt Q8MML5
EMBL AJ002382
AC123513
AAFI02000012
RefSeq XP_644036.1
ProteinModelPortal Q8MML5
STRING 44689.DDB_0185208
PRIDE Q8MML5
EnsemblProtists DDB0185208
GeneID 8619466
KEGG ddi:DDB_G0274109
dictyBase DDB_G0274109
eggNOG NOG267887
InParanoid Q8MML5
KO K05760
OMA HITHANS
Proteomes UP000002195
UP000002195
GO GO:0005938
GO:0005856
GO:0030175
GO:0032433
GO:0005925
GO:0043234
GO:0008270
GO:0016339
GO:0016477
GO:0048870
GO:0031589
GO:0043327
GO:0043326
GO:0031154
GO:0007109
GO:0006897
GO:0040011
GO:0000281
GO:0050765
GO:0045921
GO:2000249
Gene3D 2.10.110.10
InterPro IPR001781
Pfam PF00412
SMART SM00132
PROSITE PS00478
PS50023

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

acts_upstream_of_or_within

GO:2000249

regulation of actin cytoskeleton reorganization

PMID:21531871[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050765

negative regulation of phagocytosis

PMID:21531871[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048870

cell motility

PMID:19065153[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045921

positive regulation of exocytosis

PMID:21531871[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043327

chemotaxis to cAMP

PMID:21531871[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

NOT|acts_upstream_of_or_within

GO:0043326

chemotaxis to folate

PMID:21531871[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043326

chemotaxis to folate

PMID:19213599[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

PMID:21531871[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0040011

locomotion

PMID:19213599[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0040011

locomotion

PMID:16155255[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0032433

filopodium tip

PMID:18349074[5]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0031941

filamentous actin

PMID:21531871[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031589

cell-substrate adhesion

PMID:19213599[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031589

cell-substrate adhesion

PMID:19065153[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031589

cell-substrate adhesion

PMID:16155255[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031154

culmination involved in sorocarp development

PMID:19213599[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031154

culmination involved in sorocarp development

PMID:16155255[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

PMID:16155255[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0016477

cell migration

PMID:19213599[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0016477

cell migration

PMID:16155255[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0016339

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PMID:19213599[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0061952

midbody abscission

PMID:19065153[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006897

endocytosis

PMID:19213599[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

PMID:16900100[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

PMID:16155255[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0000281

mitotic cytokinesis

PMID:19065153[2]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:P08799

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0286

C

Seeded From UniProt

complete

part_of

GO:0005925

focal adhesion

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0118

C

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0138

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Pribic, J et al. (2011) Paxillin and phospholipase D interact to regulate actin-based processes in Dictyostelium discoideum. Eukaryotic Cell 10 977-84 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Nagasaki, A et al. (2009) Cell adhesion molecules regulate contractile ring-independent cytokinesis in Dictyostelium discoideum. Cell Res. 19 236-46 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Duran, MB et al. (2009) Dictyostelium discoideum paxillin regulates actin-based processes. Protist 160 221-32 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 Bukharova, T et al. (2005) Paxillin is required for cell-substrate adhesion, cell sorting and slug migration during Dictyostelium development. J. Cell. Sci. 118 4295-310 PubMed GONUTS page
  5. Patel, H et al. (2008) The multi-FERM-domain-containing protein FrmA is required for turnover of paxillin-adhesion sites during cell migration of Dictyostelium. J. Cell. Sci. 121 1159-64 PubMed GONUTS page
  6. Dormann, D & Weijer, CJ (2006) Imaging of cell migration. EMBO J. 25 3480-93 PubMed GONUTS page