DANRE:MIB1

Species (Taxon ID)	Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s)	mib1 (synonyms: mib)
Protein Name(s)	E3 ubiquitin-protein ligase mib1 Protein mind bomb
External Links
UniProt	Q804S5
EMBL	AF537301 AF506233
RefSeq	NP_775393.2
UniGene	Dr.124112
ProteinModelPortal	Q804S5
BioGrid	87906
STRING	7955.ENSDARP00000101347
PRIDE	Q804S5
GeneID	352910
KEGG	dre:352910
CTD	57534
ZFIN	ZDB-GENE-030404-2
eggNOG	COG0666
HOVERGEN	HBG068386
InParanoid	Q804S5
KO	K10645
UniPathway	UPA00143
NextBio	20812654
Proteomes	UP000000437
GO	GO:0005737 GO:0005815 GO:0005886 GO:0016874 GO:0004842 GO:0008270 GO:0007275 GO:0007219
Gene3D	1.25.40.20 3.30.40.10
InterPro	IPR002110 IPR020683 IPR010606 IPR001841 IPR013083 IPR000433
Pfam	PF00023 PF12796 PF06701 PF00569
PRINTS	PR01415
SMART	SM00248 SM00184 SM00291
SUPFAM	SSF48403
PROSITE	PS50297 PS50088 PS51416 PS50089 PS01357 PS50135

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0007219	Notch signaling pathway	PMID:12530964^[1]	ECO:0000315			P	Figure 1. ngn1 and deltaA, which are involved in Notch signaling are not as effectively restricted in mind bomb mutant embryos. Additionally, mutant embryonic cells express more huC, which is characteristic of cells that escape lateral inhibition mediated by the Notch pathway.	complete
involved_in	GO:0007219	Notch signaling pathway	PMID:17287248^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-199	P	Seeded From UniProt	complete
involved_in	GO:0007219	Notch signaling pathway	PMID:15680358^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:17196985^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:15013799^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:15013799^[5]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
contributes_to	GO:0004842	ubiquitin-protein transferase activity	PMID:17196985^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	ZFIN:ZDB-GENE-050628-1	F	Seeded From UniProt	complete
contributes_to	GO:0004842	ubiquitin-protein transferase activity	PMID:17196985^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0003408	optic cup formation involved in camera-type eye development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0003407	neural retina development	PMID:25106852^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0002244	hematopoietic progenitor cell differentiation	PMID:25714926^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	ZFIN:ZDB-GENE-040426-780	P	Seeded From UniProt	complete
involved_in	GO:0002244	hematopoietic progenitor cell differentiation	PMID:25714926^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0002090	regulation of receptor internalization	PMID:17196985^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0002064	epithelial cell development	PMID:19705151^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0002064	epithelial cell development	PMID:19705151^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-070730-2	P	Seeded From UniProt	complete
involved_in	GO:0002040	sprouting angiogenesis	PMID:26825552^[10]	ECO:0000316	genetic interaction evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-051121-1 ZFIN:ZDB-MRPHLNO-140108-1 ZFIN:ZDB-MRPHLNO-170302-2	P	Seeded From UniProt	complete
involved_in	GO:0001885	endothelial cell development	PMID:17251261^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-050209-22	P	Seeded From UniProt	complete
involved_in	GO:0001756	somitogenesis	PMID:9007237^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0001756	somitogenesis	PMID:20637620^[13]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0001756	somitogenesis	PMID:17331493^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0001756	somitogenesis	PMID:17331493^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-070730-2	P	Seeded From UniProt	complete
involved_in	GO:0001756	somitogenesis	PMID:17331493^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-070730-1	P	Seeded From UniProt	complete
involved_in	GO:0001756	somitogenesis	PMID:16225858^[15]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0001570	vasculogenesis	PMID:18377889^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0001568	blood vessel development	PMID:17251261^[11]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-050209-22	P	Seeded From UniProt	complete
part_of	GO:0000151	ubiquitin ligase complex	PMID:17196985^[4]	ECO:0000305	curator inference used in manual assertion	GO:0004842	C	Seeded From UniProt	complete
part_of	GO:0000151	ubiquitin ligase complex	PMID:15013799^[5]	ECO:0000305	curator inference used in manual assertion	GO:0004842	C	Seeded From UniProt	complete
involved_in	GO:0071599	otic vesicle development	PMID:9806913^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0071599	otic vesicle development	PMID:9007247^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0070086	ubiquitin-dependent endocytosis	PMID:26020642^[19]	ECO:0000353	physical interaction evidence used in manual assertion	ZFIN:ZDB-GENE-990415-47	P	Seeded From UniProt	complete
involved_in	GO:0061551	trigeminal ganglion development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0061195	taste bud formation	PMID:21791527^[20]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0060218	hematopoietic stem cell differentiation	PMID:19332767^[21]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-090730-4	P	Seeded From UniProt	complete
involved_in	GO:0060216	definitive hemopoiesis	PMID:25714926^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0060113	inner ear receptor cell differentiation	PMID:10572043^[22]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0060035	notochord cell development	PMID:9007234^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-241	P	Seeded From UniProt	complete
involved_in	GO:0060035	notochord cell development	PMID:9007234^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-199	P	Seeded From UniProt	complete
involved_in	GO:0051865	protein autoubiquitination	PMID:17196985^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0051865	protein autoubiquitination	PMID:17196985^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0050931	pigment cell differentiation	PMID:9007256^[24]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048920	posterior lateral line neuromast primordium migration	PMID:29078376^[25]	ECO:0000316	genetic interaction evidence used in manual assertion	ZFIN:ZDB-GENE-110208-9	P	Seeded From UniProt	complete
involved_in	GO:0048916	posterior lateral line development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048899	anterior lateral line development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048892	lateral line nerve development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048859	formation of anatomical boundary	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048793	pronephros development	PMID:17287248^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-199	P	Seeded From UniProt	complete
involved_in	GO:0048699	generation of neurons	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048699	generation of neurons	PMID:17199043^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048666	neuron development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048665	neuron fate specification	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048663	neuron fate commitment	PMID:9806913^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048546	digestive tract morphogenesis	PMID:15689380^[27]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048514	blood vessel morphogenesis	PMID:11585794^[28]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	PMID:17196985^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	ZFIN:ZDB-GENE-990415-47	C	Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	PMID:17196985^[4]	ECO:0000316	genetic interaction evidence used in manual assertion	ZFIN:ZDB-GENE-000125-4	C	Seeded From UniProt	complete
involved_in	GO:0048259	regulation of receptor-mediated endocytosis	PMID:19056830^[29]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0048259	regulation of receptor-mediated endocytosis	PMID:19056830^[29]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-090924-1	P	Seeded From UniProt	complete
involved_in	GO:0048066	developmental pigmentation	PMID:9007256^[24]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0045747	positive regulation of Notch signaling pathway	PMID:17685488^[30]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-071218-1	P	Seeded From UniProt	complete
involved_in	GO:0045747	positive regulation of Notch signaling pathway	PMID:15013799^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-020426-41	P	Seeded From UniProt	complete
involved_in	GO:0045685	regulation of glial cell differentiation	PMID:15680358^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0045664	regulation of neuron differentiation	PMID:15068793^[31]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:17196985^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0039022	pronephric duct development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0035315	hair cell differentiation	PMID:9806913^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:21262462^[32]	ECO:0000353	physical interaction evidence used in manual assertion	ZFIN:ZDB-GENE-030616-450	C	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	PMID:17331493^[14]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0031398	positive regulation of protein ubiquitination	PMID:24714733^[33]	ECO:0000353	physical interaction evidence used in manual assertion	ZFIN:ZDB-GENE-061110-94	P	Seeded From UniProt	complete
involved_in	GO:0031398	positive regulation of protein ubiquitination	PMID:24714733^[33]	ECO:0000353	physical interaction evidence used in manual assertion	ZFIN:ZDB-GENE-030826-19	P	Seeded From UniProt	complete
involved_in	GO:0031076	embryonic camera-type eye development	PMID:15680358^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0030903	notochord development	PMID:9007234^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-241	P	Seeded From UniProt	complete
involved_in	GO:0030903	notochord development	PMID:9007234^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-199	P	Seeded From UniProt	complete
involved_in	GO:0030902	hindbrain development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0030902	hindbrain development	PMID:9007238^[34]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-241	P	Seeded From UniProt	complete
involved_in	GO:0030902	hindbrain development	PMID:19705151^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0030902	hindbrain development	PMID:19705151^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-070730-2	P	Seeded From UniProt	complete
involved_in	GO:0030318	melanocyte differentiation	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0030318	melanocyte differentiation	PMID:17331493^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0030318	melanocyte differentiation	PMID:17331493^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-070730-2	P	Seeded From UniProt	complete
involved_in	GO:0030318	melanocyte differentiation	PMID:17331493^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-070730-1	P	Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:15013799^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-020426-41	P	Seeded From UniProt	complete
part_of	GO:0030139	endocytic vesicle	PMID:15013799^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0030097	hemopoiesis	PMID:25490269^[35]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-070730-7	P	Seeded From UniProt	complete
involved_in	GO:0030097	hemopoiesis	PMID:16166372^[36]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-051121-1	P	Seeded From UniProt	complete
involved_in	GO:0022008	neurogenesis	PMID:9007238^[34]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-241	P	Seeded From UniProt	complete
involved_in	GO:0021986	habenula development	PMID:17199043^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021654	rhombomere boundary formation	PMID:19705151^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021654	rhombomere boundary formation	PMID:19705151^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-070730-2	P	Seeded From UniProt	complete
involved_in	GO:0021546	rhombomere development	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021536	diencephalon development	PMID:21148001^[37]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021521	ventral spinal cord interneuron specification	PMID:17045256^[38]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021520	spinal cord motor neuron cell fate specification	PMID:9007241^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021520	spinal cord motor neuron cell fate specification	PMID:17442701^[39]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-071004-2	P	Seeded From UniProt	complete
involved_in	GO:0021519	spinal cord association neuron specification	PMID:17442701^[39]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-071004-2	P	Seeded From UniProt	complete
involved_in	GO:0021514	ventral spinal cord interneuron differentiation	PMID:24768892^[40]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-MRPHLNO-051121-1	P	Seeded From UniProt	complete
involved_in	GO:0021514	ventral spinal cord interneuron differentiation	PMID:24768892^[40]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021514	ventral spinal cord interneuron differentiation	PMID:18680739^[41]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0021510	spinal cord development	PMID:23409159^[42]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-130402-4	P	Seeded From UniProt	complete
involved_in	GO:0021508	floor plate formation	PMID:17045256^[38]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1208	P	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:17196985^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:15013799^[5]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0010001	glial cell differentiation	PMID:15013799^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-020426-41	P	Seeded From UniProt	complete
involved_in	GO:0009880	embryonic pattern specification	PMID:15366005^[43]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0008593	regulation of Notch signaling pathway	PMID:21688347^[44]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-120606-1	P	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	PMID:15944187^[45]	ECO:0000316	genetic interaction evidence used in manual assertion	ZFIN:ZDB-GENO-050811-1 ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0007507	heart development	PMID:23314057^[46]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-130419-6	P	Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:21688347^[44]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-120606-1	P	Seeded From UniProt	complete
involved_in	GO:0007417	central nervous system development	PMID:9007234^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-241	P	Seeded From UniProt	complete
involved_in	GO:0007417	central nervous system development	PMID:9007234^[23]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-199	P	Seeded From UniProt	complete
involved_in	GO:0007368	determination of left/right symmetry	PMID:17199043^[26]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0007219	Notch signaling pathway	PMID:9806913^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0007219	Notch signaling pathway	PMID:23840804^[47]	ECO:0000315	mutant phenotype evidence used in manual assertion	ZFIN:ZDB-GENO-980202-1107	P	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:21873635^[48]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2679684 PANTHER:PTN001197468	P	Seeded From UniProt	complete
involved_in	GO:0007219	Notch signaling pathway	PMID:21873635^[48]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0263601 MGI:MGI:2443157 PANTHER:PTN000653843	P	Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	PMID:21873635^[48]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0263601 PANTHER:PTN000653843	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[48]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0086442 FB:FBgn0263601 PANTHER:PTN001197468	C	Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:21873635^[48]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001197468 UniProtKB:Q96AX9 ZFIN:ZDB-GENE-030404-2	F	Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010606 InterPro:IPR037252	F	Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000433	F	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010606	P	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010606 InterPro:IPR037252	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206	C	Seeded From UniProt	complete
involved_in	GO:0007219	Notch signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0914	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0005815	microtubule organizing center	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0048	C	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Itoh, M et al. (2003) Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev. Cell 4 67-82 PubMed GONUTS page
↑ ^2.0 ^2.1 Liu, Y et al. (2007) Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros. Development 134 1111-22 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Bernardos, RL et al. (2005) Notch-Delta signaling is required for spatial patterning and Müller glia differentiation in the zebrafish retina. Dev. Biol. 278 381-95 PubMed GONUTS page
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 Zhang, C et al. (2007) Zebrafish Mib and Mib2 are mutual E3 ubiquitin ligases with common and specific delta substrates. J. Mol. Biol. 366 1115-28 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 Chen, W & Casey Corliss, D (2004) Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis. Dev. Biol. 267 361-73 PubMed GONUTS page
↑ ^6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 ^6.11 ^6.12 ^6.13 Jiang, YJ et al. (1996) Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development 123 205-16 PubMed GONUTS page
↑ Imai, F et al. (2014) Stem-loop binding protein is required for retinal cell proliferation, neurogenesis, and intraretinal axon pathfinding in zebrafish. Dev. Biol. 394 94-109 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Lin, MI et al. (2015) Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. Elife 4 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 ^9.4 ^9.5 Qiu, X et al. (2009) Temporal Notch activation through Notch1a and Notch3 is required for maintaining zebrafish rhombomere boundaries. Dev. Genes Evol. 219 339-51 PubMed GONUTS page
↑ Wang, X et al. (2016) MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Cardiovasc. Res. 110 140-50 PubMed GONUTS page
↑ ^11.0 ^11.1 Leslie, JD et al. (2007) Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis. Development 134 839-44 PubMed GONUTS page
↑ van Eeden, FJ et al. (1996) Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123 153-64 PubMed GONUTS page
↑ Herrgen, L et al. (2010) Intercellular coupling regulates the period of the segmentation clock. Curr. Biol. 20 1244-53 PubMed GONUTS page
↑ ^14.0 ^14.1 ^14.2 ^14.3 ^14.4 ^14.5 ^14.6 Zhang, C et al. (2007) The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly. Dev. Biol. 305 14-27 PubMed GONUTS page
↑ Henry, CA et al. (2005) Interactions between muscle fibers and segment boundaries in zebrafish. Dev. Biol. 287 346-60 PubMed GONUTS page
↑ Pendeville, H et al. (2008) Zebrafish Sox7 and Sox18 function together to control arterial-venous identity. Dev. Biol. 317 405-16 PubMed GONUTS page
↑ ^17.0 ^17.1 ^17.2 ^17.3 Haddon, C et al. (1998) Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the mind bomb mutant. Development 125 4637-44 PubMed GONUTS page
↑ Malicki, J et al. (1996) Mutations affecting development of the zebrafish ear. Development 123 275-83 PubMed GONUTS page
↑ Palardy, G & Chitnis, AB (2015) Identification of the Mind Bomb1 Interaction Domain in Zebrafish DeltaD. PLoS ONE 10 e0127864 PubMed GONUTS page
↑ Kapsimali, M et al. (2011) Fgf signaling controls pharyngeal taste bud formation through miR-200 and Delta-Notch activity. Development 138 3473-84 PubMed GONUTS page
↑ Burns, CE et al. (2009) A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood 113 5776-82 PubMed GONUTS page
↑ Riley, BB et al. (1999) The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by pax2.1. Development 126 5669-78 PubMed GONUTS page
↑ ^23.0 ^23.1 ^23.2 ^23.3 ^23.4 ^23.5 Stemple, DL et al. (1996) Mutations affecting development of the notochord in zebrafish. Development 123 117-28 PubMed GONUTS page
↑ ^24.0 ^24.1 Kelsh, RN et al. (1996) Zebrafish pigmentation mutations and the processes of neural crest development. Development 123 369-89 PubMed GONUTS page
↑ Mizoguchi, T et al. (2017) Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc. Natl. Acad. Sci. U.S.A. 114 E9280-E9289 PubMed GONUTS page
↑ ^26.0 ^26.1 ^26.2 Aizawa, H et al. (2007) Temporally regulated asymmetric neurogenesis causes left-right difference in the zebrafish habenular structures. Dev. Cell 12 87-98 PubMed GONUTS page
↑ Crosnier, C et al. (2005) Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine. Development 132 1093-104 PubMed GONUTS page
↑ Lawson, ND et al. (2001) Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128 3675-83 PubMed GONUTS page
↑ ^29.0 ^29.1 Matsuda, M & Chitnis, AB (2009) Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue. Development 136 197-206 PubMed GONUTS page
↑ Del Monte, G et al. (2007) Monitoring Notch1 activity in development: evidence for a feedback regulatory loop. Dev. Dyn. 236 2594-614 PubMed GONUTS page
↑ Cheng, YC et al. (2004) Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain. Dev. Cell 6 539-50 PubMed GONUTS page
↑ Ohata, S et al. (2011) Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells. Neuron 69 215-30 PubMed GONUTS page
↑ ^33.0 ^33.1 Tseng, LC et al. (2014) New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens. PLoS ONE 9 e93394 PubMed GONUTS page
↑ ^34.0 ^34.1 Schier, AF et al. (1996) Mutations affecting the development of the embryonic zebrafish brain. Development 123 165-78 PubMed GONUTS page
↑ Sawamiphak, S et al. (2014) Interferon gamma signaling positively regulates hematopoietic stem cell emergence. Dev. Cell 31 640-53 PubMed GONUTS page
↑ Burns, CE et al. (2005) Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 19 2331-42 PubMed GONUTS page
↑ Mahler, J et al. (2010) DeltaA/DeltaD regulate multiple and temporally distinct phases of notch signaling during dopaminergic neurogenesis in zebrafish. J. Neurosci. 30 16621-35 PubMed GONUTS page
↑ ^38.0 ^38.1 Schäfer, M et al. (2007) Discontinuous organization and specification of the lateral floor plate in zebrafish. Dev. Biol. 301 117-29 PubMed GONUTS page
↑ ^39.0 ^39.1 Shin, J et al. (2007) Notch signaling regulates neural precursor allocation and binary neuronal fate decisions in zebrafish. Development 134 1911-20 PubMed GONUTS page
↑ ^40.0 ^40.1 Okigawa, S et al. (2014) Different combinations of Notch ligands and receptors regulate V2 interneuron progenitor proliferation and V2a/V2b cell fate determination. Dev. Biol. 391 196-206 PubMed GONUTS page
↑ Batista, MF et al. (2008) Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneurons. Dev. Biol. 322 263-75 PubMed GONUTS page
↑ Kondrychyn, I et al. (2013) Stretching morphogenesis of the roof plate and formation of the central canal. PLoS ONE 8 e56219 PubMed GONUTS page
↑ Riley, BB et al. (2004) Rhombomere boundaries are Wnt signaling centers that regulate metameric patterning in the zebrafish hindbrain. Dev. Dyn. 231 278-91 PubMed GONUTS page
↑ ^44.0 ^44.1 Hortopan, GA & Baraban, SC (2011) Aberrant expression of genes necessary for neuronal development and Notch signaling in an epileptic mind bomb zebrafish. Dev. Dyn. 240 1964-76 PubMed GONUTS page
↑ Yamaguchi, M et al. (2005) Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development 132 3027-43 PubMed GONUTS page
↑ Luxán, G et al. (2013) Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat. Med. 19 193-201 PubMed GONUTS page
↑ Pascoal, S et al. (2013) Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish. PLoS ONE 8 e68021 PubMed GONUTS page
↑ ^48.0 ^48.1 ^48.2 ^48.3 ^48.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:12530964-1] Itoh, M et al. (2003) Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev. Cell 4 67-82 PubMed GONUTS page

[PMID:17287248-2] 2.0 ^2.1 Liu, Y et al. (2007) Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros. Development 134 1111-22 PubMed GONUTS page

[PMID:15680358-3] 3.0 ^3.1 ^3.2 Bernardos, RL et al. (2005) Notch-Delta signaling is required for spatial patterning and Müller glia differentiation in the zebrafish retina. Dev. Biol. 278 381-95 PubMed GONUTS page

[PMID:17196985-4] 4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 Zhang, C et al. (2007) Zebrafish Mib and Mib2 are mutual E3 ubiquitin ligases with common and specific delta substrates. J. Mol. Biol. 366 1115-28 PubMed GONUTS page

[PMID:15013799-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 ^5.6 ^5.7 Chen, W & Casey Corliss, D (2004) Three modules of zebrafish Mind bomb work cooperatively to promote Delta ubiquitination and endocytosis. Dev. Biol. 267 361-73 PubMed GONUTS page

[PMID:9007241-6] 6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 ^6.11 ^6.12 ^6.13 Jiang, YJ et al. (1996) Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development 123 205-16 PubMed GONUTS page

[PMID:25106852-7] Imai, F et al. (2014) Stem-loop binding protein is required for retinal cell proliferation, neurogenesis, and intraretinal axon pathfinding in zebrafish. Dev. Biol. 394 94-109 PubMed GONUTS page

[PMID:25714926-8] 8.0 ^8.1 ^8.2 Lin, MI et al. (2015) Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling. Elife 4 PubMed GONUTS page

[PMID:19705151-9] 9.0 ^9.1 ^9.2 ^9.3 ^9.4 ^9.5 Qiu, X et al. (2009) Temporal Notch activation through Notch1a and Notch3 is required for maintaining zebrafish rhombomere boundaries. Dev. Genes Evol. 219 339-51 PubMed GONUTS page

[PMID:26825552-10] Wang, X et al. (2016) MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis. Cardiovasc. Res. 110 140-50 PubMed GONUTS page

[PMID:17251261-11] 11.0 ^11.1 Leslie, JD et al. (2007) Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis. Development 134 839-44 PubMed GONUTS page

[PMID:9007237-12] van Eeden, FJ et al. (1996) Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development 123 153-64 PubMed GONUTS page

[PMID:20637620-13] Herrgen, L et al. (2010) Intercellular coupling regulates the period of the segmentation clock. Curr. Biol. 20 1244-53 PubMed GONUTS page

[PMID:17331493-14] 14.0 ^14.1 ^14.2 ^14.3 ^14.4 ^14.5 ^14.6 Zhang, C et al. (2007) The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly. Dev. Biol. 305 14-27 PubMed GONUTS page

[PMID:16225858-15] Henry, CA et al. (2005) Interactions between muscle fibers and segment boundaries in zebrafish. Dev. Biol. 287 346-60 PubMed GONUTS page

[PMID:18377889-16] Pendeville, H et al. (2008) Zebrafish Sox7 and Sox18 function together to control arterial-venous identity. Dev. Biol. 317 405-16 PubMed GONUTS page

[PMID:9806913-17] 17.0 ^17.1 ^17.2 ^17.3 Haddon, C et al. (1998) Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the mind bomb mutant. Development 125 4637-44 PubMed GONUTS page

[PMID:9007247-18] Malicki, J et al. (1996) Mutations affecting development of the zebrafish ear. Development 123 275-83 PubMed GONUTS page

[PMID:26020642-19] Palardy, G & Chitnis, AB (2015) Identification of the Mind Bomb1 Interaction Domain in Zebrafish DeltaD. PLoS ONE 10 e0127864 PubMed GONUTS page

[PMID:21791527-20] Kapsimali, M et al. (2011) Fgf signaling controls pharyngeal taste bud formation through miR-200 and Delta-Notch activity. Development 138 3473-84 PubMed GONUTS page

[PMID:19332767-21] Burns, CE et al. (2009) A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood 113 5776-82 PubMed GONUTS page

[PMID:10572043-22] Riley, BB et al. (1999) The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by pax2.1. Development 126 5669-78 PubMed GONUTS page

[PMID:9007234-23] 23.0 ^23.1 ^23.2 ^23.3 ^23.4 ^23.5 Stemple, DL et al. (1996) Mutations affecting development of the notochord in zebrafish. Development 123 117-28 PubMed GONUTS page

[PMID:9007256-24] 24.0 ^24.1 Kelsh, RN et al. (1996) Zebrafish pigmentation mutations and the processes of neural crest development. Development 123 369-89 PubMed GONUTS page

[PMID:29078376-25] Mizoguchi, T et al. (2017) Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc. Natl. Acad. Sci. U.S.A. 114 E9280-E9289 PubMed GONUTS page

[PMID:17199043-26] 26.0 ^26.1 ^26.2 Aizawa, H et al. (2007) Temporally regulated asymmetric neurogenesis causes left-right difference in the zebrafish habenular structures. Dev. Cell 12 87-98 PubMed GONUTS page

[PMID:15689380-27] Crosnier, C et al. (2005) Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine. Development 132 1093-104 PubMed GONUTS page

[PMID:11585794-28] Lawson, ND et al. (2001) Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128 3675-83 PubMed GONUTS page

[PMID:19056830-29] 29.0 ^29.1 Matsuda, M & Chitnis, AB (2009) Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue. Development 136 197-206 PubMed GONUTS page

[PMID:17685488-30] Del Monte, G et al. (2007) Monitoring Notch1 activity in development: evidence for a feedback regulatory loop. Dev. Dyn. 236 2594-614 PubMed GONUTS page

[PMID:15068793-31] Cheng, YC et al. (2004) Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain. Dev. Cell 6 539-50 PubMed GONUTS page

[PMID:21262462-32] Ohata, S et al. (2011) Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells. Neuron 69 215-30 PubMed GONUTS page

[PMID:24714733-33] 33.0 ^33.1 Tseng, LC et al. (2014) New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens. PLoS ONE 9 e93394 PubMed GONUTS page

[PMID:9007238-34] 34.0 ^34.1 Schier, AF et al. (1996) Mutations affecting the development of the embryonic zebrafish brain. Development 123 165-78 PubMed GONUTS page

[PMID:25490269-35] Sawamiphak, S et al. (2014) Interferon gamma signaling positively regulates hematopoietic stem cell emergence. Dev. Cell 31 640-53 PubMed GONUTS page

[PMID:16166372-36] Burns, CE et al. (2005) Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 19 2331-42 PubMed GONUTS page

[PMID:21148001-37] Mahler, J et al. (2010) DeltaA/DeltaD regulate multiple and temporally distinct phases of notch signaling during dopaminergic neurogenesis in zebrafish. J. Neurosci. 30 16621-35 PubMed GONUTS page

[PMID:17045256-38] 38.0 ^38.1 Schäfer, M et al. (2007) Discontinuous organization and specification of the lateral floor plate in zebrafish. Dev. Biol. 301 117-29 PubMed GONUTS page

[PMID:17442701-39] 39.0 ^39.1 Shin, J et al. (2007) Notch signaling regulates neural precursor allocation and binary neuronal fate decisions in zebrafish. Development 134 1911-20 PubMed GONUTS page

[PMID:24768892-40] 40.0 ^40.1 Okigawa, S et al. (2014) Different combinations of Notch ligands and receptors regulate V2 interneuron progenitor proliferation and V2a/V2b cell fate determination. Dev. Biol. 391 196-206 PubMed GONUTS page

[PMID:18680739-41] Batista, MF et al. (2008) Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneurons. Dev. Biol. 322 263-75 PubMed GONUTS page

[PMID:23409159-42] Kondrychyn, I et al. (2013) Stretching morphogenesis of the roof plate and formation of the central canal. PLoS ONE 8 e56219 PubMed GONUTS page

[PMID:15366005-43] Riley, BB et al. (2004) Rhombomere boundaries are Wnt signaling centers that regulate metameric patterning in the zebrafish hindbrain. Dev. Dyn. 231 278-91 PubMed GONUTS page

[PMID:21688347-44] 44.0 ^44.1 Hortopan, GA & Baraban, SC (2011) Aberrant expression of genes necessary for neuronal development and Notch signaling in an epileptic mind bomb zebrafish. Dev. Dyn. 240 1964-76 PubMed GONUTS page

[PMID:15944187-45] Yamaguchi, M et al. (2005) Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development 132 3027-43 PubMed GONUTS page

[PMID:23314057-46] Luxán, G et al. (2013) Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat. Med. 19 193-201 PubMed GONUTS page

[PMID:23840804-47] Pascoal, S et al. (2013) Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish. PLoS ONE 8 e68021 PubMed GONUTS page

[PMID:21873635-48] 48.0 ^48.1 ^48.2 ^48.3 ^48.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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DANRE:MIB1

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