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DANRE:MIB1

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) mib1 (synonyms: mib)
Protein Name(s) E3 ubiquitin-protein ligase mib1

Protein mind bomb

External Links
UniProt Q804S5
EMBL AF537301
AF506233
RefSeq NP_775393.2
UniGene Dr.124112
ProteinModelPortal Q804S5
BioGrid 87906
STRING 7955.ENSDARP00000101347
PRIDE Q804S5
GeneID 352910
KEGG dre:352910
CTD 57534
ZFIN ZDB-GENE-030404-2
eggNOG COG0666
HOVERGEN HBG068386
InParanoid Q804S5
KO K10645
UniPathway UPA00143
NextBio 20812654
Proteomes UP000000437
GO GO:0005737
GO:0005815
GO:0005886
GO:0016874
GO:0004842
GO:0008270
GO:0007275
GO:0007219
Gene3D 1.25.40.20
3.30.40.10
InterPro IPR002110
IPR020683
IPR010606
IPR001841
IPR013083
IPR000433
Pfam PF00023
PF12796
PF06701
PF00569
PRINTS PR01415
SMART SM00248
SM00184
SM00291
SUPFAM SSF48403
PROSITE PS50297
PS50088
PS51416
PS50089
PS01357
PS50135

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0007219

Notch signaling pathway

PMID:12530964[1]

IMP: Inferred from Mutant Phenotype

P

Figure 1. ngn1 and deltaA, which are involved in Notch signaling are not as effectively restricted in mind bomb mutant embryos. Additionally, mutant embryonic cells express more huC, which is characteristic of cells that escape lateral inhibition mediated by the Notch pathway.

complete

GO:0004842

ubiquitin-protein ligase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

F

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

complete

GO:0004842

ubiquitin-protein transferase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

F

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

complete

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

complete

GO:0005815

microtubule organizing center

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0048

C

Seeded From UniProt

complete

GO:0007219

Notch signaling pathway

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0914

P

complete

GO:0005856

cytoskeleton

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

complete

GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000433

F

complete

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001841

F

complete

GO:0007219

Notch signaling pathway

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0914

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

complete

GO:0007275

multicellular organismal development

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

GO:0016567

protein ubiquitination

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

P

complete

GO:0008270

zinc ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000433
InterPro:IPR001841

F

Seeded From UniProt

complete

GO:0016874

ligase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0436

F

complete

GO:0046872

metal ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

F

complete

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

complete

GO:0016567

protein ubiquitination

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

P

Seeded From UniProt

complete

GO:0016567

protein ubiquitination

GO_REF:0000041

IEA: Inferred from Electronic Annotation

UniPathway:UPA00143

P

Seeded From UniProt

complete

GO:0016874

ligase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010606

F

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Itoh, M et al. (2003) Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev. Cell 4 67-82 PubMed GONUTS page