GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0097029 ! mature conventional dendritic cell differentiation
name: mature conventional dendritic cell differentiation
namespace: biological_process
def: "The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells." [GOC:BHF, PMID:15845453]
comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.
is_a: GO:0002573 ! myeloid leukocyte differentiation
is_a: GO:0097028 ! dendritic cell differentiation
AmiGO
<GOterm>GO:0097029</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
