CHICK:Q5F4D0

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	F2RL1 (ECO:0000313 with Ensembl:ENSGALP00000024125)
Protein Name(s)	Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000024125)
External Links
UniProt	Q5F4D0
EMBL	AC202799 AJ851370
RefSeq	NP_001012626.1
UniGene	Gga.22196
STRING	9031.ENSGALP00000024125
Ensembl	ENSGALT00000024171
GeneID	427213
KEGG	gga:427213
CTD	2150
eggNOG	NOG145128
GeneTree	ENSGT00760000119001
HOGENOM	HOG000116291
HOVERGEN	HBG105658
KO	K04234
OMA	LSMYLIC
OrthoDB	EOG7DNNVR
PhylomeDB	Q5F4D0
TreeFam	TF330775
Reactome	REACT_249636 REACT_250082
NextBio	20828504
PRO	PR:Q5F4D0
Proteomes	UP000000539
GO	GO:0005887 GO:0031143 GO:0015057 GO:0007596 GO:0035926 GO:0051607 GO:0061028 GO:0072643 GO:0050702 GO:0072608 GO:0050900 GO:0070661 GO:0097029 GO:0090198 GO:0046329 GO:0034140 GO:0010804 GO:0042119 GO:0030836 GO:0002741 GO:0007204 GO:0043311 GO:0070374 GO:0043123 GO:2000778 GO:2000484 GO:0046330 GO:0002690 GO:0070963 GO:0060100 GO:0014068 GO:0050927 GO:0031274 GO:1900135 GO:0035025 GO:0032930 GO:0034137 GO:0034141 GO:0034145 GO:0045944 GO:0045909 GO:0030193 GO:0002286
InterPro	IPR000276 IPR017452 IPR002281 IPR003912
Pfam	PF00001
PRINTS	PR00237 PR01428 PR01152
PROSITE	PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000660850 RGD:2586	P	Seeded From UniProt	complete
involved_in	GO:0035025	positive regulation of Rho protein signal transduction	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101802 MGI:MGI:101910 PANTHER:PTN000660850 UniProtKB:P55085 UniProtKB:Q9Y2T6	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1929509 PANTHER:PTN000660850 UniProtKB:P55085 UniProtKB:Q99678 UniProtKB:Q9HC97 UniProtKB:Q9Y2T6	C	Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101802 MGI:MGI:101910 MGI:MGI:2441992 PANTHER:PTN000660850 UniProtKB:P55085 UniProtKB:Q8IYL9 UniProtKB:Q99678 UniProtKB:Q9HC97	F	Seeded From UniProt	complete
involved_in	GO:2000778	positive regulation of interleukin-6 secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:2000484	positive regulation of interleukin-8 secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0097029	mature conventional dendritic cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0090198	negative regulation of chemokine secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0090195	chemokine secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0072608	interleukin-10 secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0070963	positive regulation of neutrophil mediated killing of gram-negative bacterium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0061028	establishment of endothelial barrier	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0060100	positive regulation of phagocytosis, engulfment	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0050927	positive regulation of positive chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0050900	leukocyte migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0050702	interleukin-1 beta secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0046330	positive regulation of JNK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0046329	negative regulation of JNK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0046328	regulation of JNK cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0045217	cell-cell junction maintenance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0043311	positive regulation of eosinophil degranulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0042119	neutrophil activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0035926	chemokine (C-C motif) ligand 2 secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0035025	positive regulation of Rho protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0032930	positive regulation of superoxide anion generation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0030836	positive regulation of actin filament depolymerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0030193	regulation of blood coagulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	C	Seeded From UniProt	complete
part_of	GO:0005769	early endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	C	Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	F	Seeded From UniProt	complete
involved_in	GO:0002741	positive regulation of cytokine secretion involved in immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:0002690	positive regulation of leukocyte chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55085 ensembl:ENSP00000296677	P	Seeded From UniProt	complete
involved_in	GO:1900135	positive regulation of renin secretion into blood stream	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0097755	positive regulation of blood vessel diameter	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0097029	mature conventional dendritic cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0090195	chemokine secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0072643	interferon-gamma secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0070661	leukocyte proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0050921	positive regulation of chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0035025	positive regulation of Rho protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
enables	GO:0031681	G-protein beta-subunit binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	F	Seeded From UniProt	complete
involved_in	GO:0031274	positive regulation of pseudopodium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
part_of	GO:0031143	pseudopodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	C	Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
involved_in	GO:0007204	positive regulation of cytosolic calcium ion concentration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	F	Seeded From UniProt	complete
involved_in	GO:0002286	T cell activation involved in immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	P	Seeded From UniProt	complete
enables	GO:0001965	G-protein alpha-subunit binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P55086 ensembl:ENSMUSP00000022185	F	Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	P	Seeded From UniProt	complete
involved_in	GO:0007596	blood coagulation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003912	P	Seeded From UniProt	complete
enables	GO:0015057	thrombin-activated receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002281 InterPro:IPR003912	F	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR002281 InterPro:IPR003912 InterPro:IPR017452	C	Seeded From UniProt	complete
involved_in	GO:0070493	thrombin-activated receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002281 InterPro:IPR003912	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

CHICK:Q5F4D0

Contents

Annotations

Notes

References

a

b

c

d

e

g

i

l

m

n

o

p

r

s

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools