Category:GO:0045841 ! negative regulation of mitotic metaphase/anaphase transition

id: GO:0045841

name: negative regulation of mitotic metaphase/anaphase transition
namespace: biological_process
def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." [GOC:go_curators]
synonym: "down regulation of mitotic metaphase/anaphase transition" EXACT []
synonym: "down-regulation of mitotic metaphase/anaphase transition" EXACT []
synonym: "downregulation of mitotic metaphase/anaphase transition" EXACT []
synonym: "inhibition of mitotic metaphase/anaphase transition" NARROW []
is_a: GO:0030071 ! regulation of mitotic metaphase/anaphase transition
is_a: GO:0045839 ! negative regulation of mitotic nuclear division
is_a: GO:1901991 ! negative regulation of mitotic cell cycle phase transition
is_a: GO:1902100 ! negative regulation of metaphase/anaphase transition of cell cycle
is_a: GO:2000816 ! negative regulation of mitotic sister chromatid separation
relationship: negatively_regulates: GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle
intersection_of: GO:0065007 ! biological regulation
intersection_of: negatively_regulates GO:0007091 ! metaphase/anaphase transition of mitotic cell cycle

AmiGO <GOterm>GO:0045841</GOterm>
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