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Category:GO:0034098 ! VCP-NPL4-UFD1 AAA ATPase complex
name: VCP-NPL4-UFD1 AAA ATPase complex
namespace: cellular_component
def: "A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry)." [PMID:11813000, PMID:16179952]
synonym: "Cdc48p-Npl4p-Ufd1p AAA ATPase complex" NARROW []
synonym: "p97-Ufd1-Npl4 complex" EXACT [PMID:12847084]
is_a: GO:0098796 ! membrane protein complex
is_a: GO:0140534 ! endoplasmic reticulum protein-containing complex
relationship: has_part: GO:0036501 ! UFD1-NPL4 complex
relationship: part_of: GO:0005789 ! endoplasmic reticulum membrane
AmiGO
<GOterm>GO:0034098</GOterm>
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