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CHICK:REL

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) REL
Protein Name(s) Proto-oncogene c-Rel

p68

External Links
UniProt P16236
EMBL X52193
M26381
PIR A34098
S10893
RefSeq NP_001161198.1
UniGene Gga.10724
PDB 1GJI
PDBsum 1GJI
ProteinModelPortal P16236
SMR P16236
STRING 9031.ENSGALP00000012728
PaxDb P16236
GeneID 396500
KEGG gga:396500
CTD 5966
eggNOG NOG119056
HOGENOM HOG000264257
HOVERGEN HBG017916
InParanoid P16236
KO K09254
PhylomeDB P16236
EvolutionaryTrace P16236
NextBio 20816539
Proteomes UP000000539
GO GO:0005737
GO:0005634
GO:0003677
GO:0046982
GO:0042803
GO:0003700
GO:0006309
Gene3D 2.60.40.10
2.60.40.340
InterPro IPR013783
IPR014756
IPR002909
IPR000451
IPR008967
IPR011539
Pfam PF00554
PRINTS PR00057
SMART SM00429
SUPFAM SSF49417
SSF81296
PROSITE PS01204
PS50254

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006309

apoptotic DNA fragmentation

PMID:9372964[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:9372964[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0011274
FB:FBgn0260632
MGI:MGI:103289
PANTHER:PTN000652441
UniProtKB:Q04206
UniProtKB:Q04864

P

Seeded From UniProt

complete

involved_in

GO:0038061

NIK/NF-kappaB signaling

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103289
PANTHER:PTN000652441

P

Seeded From UniProt

complete

involved_in

GO:0034097

response to cytokine

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000652441
RGD:727889

P

Seeded From UniProt

complete

involved_in

GO:0007249

I-kappaB kinase/NF-kappaB signaling

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000652441
RGD:1311231

P

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000652441
UniProtKB:Q04206

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103289
MGI:MGI:103290
PANTHER:PTN000652441
RGD:727889
UniProtKB:Q01201
UniProtKB:Q04206

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000652441
UniProtKB:Q01201

C

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103290
PANTHER:PTN000652441
UniProtKB:Q04206

F

Seeded From UniProt

complete

enables

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000652441
ZFIN:ZDB-GENE-040825-4

F

Seeded From UniProt

complete

enables

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260632
MGI:MGI:103290
PANTHER:PTN000652441
UniProtKB:Q04206

F

Seeded From UniProt

complete

involved_in

GO:0000122

negative regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103290
PANTHER:PTN000652441
UniProtKB:Q04206

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011539
InterPro:IPR037059

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000451
InterPro:IPR008967
InterPro:IPR011539
InterPro:IPR030505
InterPro:IPR037059

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000451
InterPro:IPR030505

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000451
InterPro:IPR030505

C

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000451
InterPro:IPR008967
InterPro:IPR011539
InterPro:IPR037059

P

Seeded From UniProt

complete

involved_in

GO:0007249

I-kappaB kinase/NF-kappaB signaling

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030505

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030505

P

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:9372964[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:9372964[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:9372964[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:9372964[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 You, M et al. (1997) ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol. Cell. Biol. 17 7328-41 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page